Biological Effects of Dietary Lectins

A. Pusztai

Biological Effects of Dietary Lectins

于Recent advances of research in antinutritional factors in legume seeds

著者：

A. Pusztai

A. Pusztai Rowett Research Institute, Bucksburn, Aberdeen, AB2 9SB, Scotland, UK

Search for other papers by A. Pusztai in
Current site
Google Scholar
PubMed

类型:: 章节

Page Range:: 17–29

DOI:: https://doi.org/10.1163/9789004684690_005

Purchase instant access (PDF download and unlimited online access):

€42.00€35.00 excl. VAT

Add to Cart

找回访问令牌

Summary

Most dietary lectins are resistant to gut proteolysis to an appreciable but variable extent. By binding to membrane receptors of epithelial cells of the small intestine and subsequent endocytosis, lectins may interfere with the digestion and absorption of nutrients, increase wasteful protein and glycoprotein synthesis and secretion, speed up cellular turnover, cause hyperplasia and modify gut immune function. A combination of some or all of these effects reduces the efficiency of nutrient utilization. As a proportion of all dietary lectins, even those which are relatively non-toxic, is systemically absorbed, lectins may affect immunity, the endocrine system and general metabolism. Thus, both soya (SBL) and kidney bean (PHA) lectins reduce blood insulin concentration for the entire period of feeding, while glucagon levels are increased by PHA. As, despite low insulin levels, rats maintain near normal blood sugar concentrations, other endocrine organs and their hormone secretion may also be affected by PHA. The net result of all the changes in hormone levels shifts the balance of general metabolism towards increased catabolism i.e. increased lipolysis, muscle breakdown and mobilization of liver glycogen. Accordingly, through the direct effects of systemically absorbed lectins or, indirectly, through the modulation of the endocrine system by gut hormones, all lectins introduced into the alimentary tract may interfere with metabolic processes of the body. With most lectins studied to date the changes induced lead to increased catabolic breakdown of all body components, proteins, lipids and carbohydrates, retard growth and affect health.

引用信息

Save
Cite
Email this content

Share Link

Copy this link, or click below to email it to a friend
Email this content
or copy the link directly:

https://brill.edhh.ma/abstract/book/9789004684690/B9789004684690_s005.xml
The link was not copied. Your current browser may not support copying via this button.

Link copied successfully

折叠
展开
回到页面顶端

Recent advances of research in antinutritional factors in legume seeds

Proceedings of the first international workshop on ANF in legume seeds, Wageningen 23-25 nov. '88

ISBN:: 9789004684690

出版社:: Wageningen Academic

印刷出版日期:: 01 Jan 1989

Subjects
- Life Sciences

Front Matter

Show Items

Back Matter

Show Items

统计数据

	全部期间	过去一年	过去30天
摘要浏览次数	60	60	23
全文浏览次数	1	1	0
PDF下载次数	1	1	0

African Studies	Education	Media Studies
American Studies	History	Middle East and Islamic Studies
Ancient Near East and Egypt	Human Rights and Humanitarian Law	Musicology
Art History	International Law	Philosophy
Asian Studies	International Relations	Religious Studies
Biblical Studies	Jewish Studies	Slavic and Eurasian Studies
Biology	Languages and Linguistics	Social Sciences
Book History and Cartography	Life Sciences	Theology and World Christianity
Classical Studies	Literature and Cultural Studies

Subjects

AppBar-Authors 2025

AppBar-Open Access 2025

AppBar-Product Information 2025

AppBar-Company 2025

AppBar-Contact 2025

Biological Effects of Dietary Lectins

Summary

引用信息

Share Link

Recent advances of research in antinutritional factors in legume seeds

Proceedings of the first international workshop on ANF in legume seeds, Wageningen 23-25 nov. '88

目录

统计数据

统计数据