Effect of Soybean Trypsin Inhibitor [Bowman-Birk] on the Exocrine Secretion of the Human Pancreas

A.R. Deshmukh; I.E. Liener; R.L. Goodale

Effect of Soybean Trypsin Inhibitor [Bowman-Birk] on the Exocrine Secretion of the Human Pancreas

In: Recent advances of research in antinutritional factors in legume seeds

Authors:

A.R. Deshmukh

A.R. Deshmukh University of Minnesota, St. Paul/Minneapolis, MN, U.S.A.

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I.E. Liener

I.E. Liener University of Minnesota, St. Paul/Minneapolis, MN, U.S.A.

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R.L. Goodale

R.L. Goodale University of Minnesota, St. Paul/Minneapolis, MN, U.S.A.

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Type:: Chapter

Pages:: 129–132

DOI:: https://doi.org/10.1163/9789004684690_027

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Summary

This study was undertaken to clarify the issue whether feedback regulation of pancreatic enzyme secretion occurs in human beings. Bowman-Birk inhibitor from soybean was used to inhibit the activities of trypsin and chymotrypsin. Pure pancreatic juice was collected by endoscopic retrograde cholangiopancreatography. Levels of enzymes studied, trypsin, chymotrypsin, elastase, and amylase, were increased in output and concentration two to threefolds. The results confirmed the existence of feedback control of pancreas in humans.

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Recent advances of research in antinutritional factors in legume seeds

Proceedings of the first international workshop on ANF in legume seeds, Wageningen 23-25 nov. '88

E-Book ISBN:: 9789004684690

Publisher:: Wageningen Academic

Print Publication Date:: 01 Jan 1989

Subjects
- Life Sciences

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Effect of Soybean Trypsin Inhibitor [Bowman-Birk] on the Exocrine Secretion of the Human Pancreas

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Citation Info

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Recent advances of research in antinutritional factors in legume seeds

Proceedings of the first international workshop on ANF in legume seeds, Wageningen 23-25 nov. '88

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