Lactobacilli and its metabolites as potential probiotics against Gardnerella vaginalis

C. Felgueiras; T.B. Cereija; A. Machado; N. Cerca; L.R. Rodrigues

Lactobacilli and its metabolites as potential probiotics against Gardnerella vaginalis

in Industrial, medical and environmental applications of microorganisms

Autor:innen:

C. Felgueiras

C. Felgueiras CEB-IBB, Campus de Gualtar, Universidade do Minho, Braga, Portugal; nunocerca@ceb.uminho.pt

Search for other papers by C. Felgueiras in
Current site
Google Scholar
PubMed

T.B. Cereija

T.B. Cereija CEB-IBB, Campus de Gualtar, Universidade do Minho, Braga, Portugal; nunocerca@ceb.uminho.pt

Search for other papers by T.B. Cereija in
Current site
Google Scholar
PubMed

A. Machado

A. Machado CEB-IBB, Campus de Gualtar, Universidade do Minho, Braga, Portugal; nunocerca@ceb.uminho.pt

Search for other papers by A. Machado in
Current site
Google Scholar
PubMed

N. Cerca

N. Cerca CEB-IBB, Campus de Gualtar, Universidade do Minho, Braga, Portugal; nunocerca@ceb.uminho.pt

Search for other papers by N. Cerca in
Current site
Google Scholar
PubMed

, und

L.R. Rodrigues

L.R. Rodrigues CEB-IBB, Campus de Gualtar, Universidade do Minho, Braga, Portugal; nunocerca@ceb.uminho.pt

Search for other papers by L.R. Rodrigues in
Current site
Google Scholar
PubMed

Art:: Kapitel

Seiten:: 541–546

DOI:: https://doi.org/10.3920/9789086867950_096

Über Institut einloggen

Sofortzugang erwerben (PDF-Download und unbegrenzter Online-Zugang):

42,00 €35,00 € excl. VAT

Add to Cart

Token einlösen

Bacterial vaginosis (BV) is one of the most common gynecological disorder affecting women in reproductive age. Current BV treatment is strictly based in antibiotic therapy but has result in an increased resistance of BV anaerobes, especially Gardnerella vaginalis. One alternative therapy for BV is the recolonisation of vagina with lactobacilli species. Our goal was to evaluate the probiotic potential of intra and extracellular metabolites from a broad range of lactobacilli strains against several G. vaginalis strains. To accomplish our goal, we isolated 60 vaginal lactobacilli strains from healthy women and performed a screening by an agar spot test against 9 G. vaginalis strains. We also included 30 colection strains. For the best candidates we determined the minimum inhibitory concentration and identified the lactobacilli metabolites responsible for G. vaginalis growth inhibition. Overall, from the 90 lactobacilli strains tested, only 4 culture collection and 3 clinical isolate lactobacilli strains exhibited a broad probiotic activity against all the G. vaginalis strains tested. Therefore, our data suggests the existence of non-vaginal lactobacilli strains possessing probiotic activity against numerous G. vaginalis strains, which may contribute for a new and more effective BV treatment than the currently used therapies.

Zitierungsangaben

Save
Cite
Inhalt per Mail versenden

Link teilen

Sie können einen Link zu dieser Seite per E-Mail senden:
Inhalt per Mail versenden
oder den Link direkt kopieren:

https://brill.edhh.ma/configurable/content/book$002f9789086867950$002fBP000096.xml
Der Link wurde nicht kopiert. Ihr aktueller Browser unterstützt das Kopieren über diese Schaltfläche möglicherweise nicht.

Link wurde kopiert

Reduzieren
Erweitern
Nach oben

Industrial, medical and environmental applications of microorganisms

Current status and trends

ISBN:: 9789086867950

Verleger:: Wageningen Academic

Print-Publikationsdatum:: 01 Nov 2014

Fachgebiete
- Biowissenschaften

Kennzahlen

	Insgesamt	Letzte 365 Tage	In den letzten 30 Tagen
Aufrufe von Kurzbeschreibungen	131	59	18
Gesamttextansichten	6	0	0
PDF-Downloads	1	0	0

Afrikanistik	Internationale Beziehungen	Nahost- und Islamwissenschaften
Altorientalistik und Ägyptologie	Internationales Recht	Pädagogik
Amerikanistik	Judaistik	Philosophie
Asienwissenschaften	Klassische Altertumswissenschaft	Religionswissenschaft
Bibelauslegung	Kunstgeschichte	Slawistik und Eurasienkunde
Biologie	Literatur- und Kulturwissenschaften	Sozialwissenschaften
Biowissenschaften	Medienwissenschaft	Sprachen und Linguistik
Buchgeschichte und Kartographie	Menschenrechte und humanitäres Völkerrecht	Theologie und Christentum
Geschichte	Musikwissenschaft

Fachgebiete

Autor:innen

Open Access

Produkt-Informationen

Über uns

Kontakt

Lactobacilli and its metabolites as potential probiotics against Gardnerella vaginalis

Zitierungsangaben

Link teilen

Industrial, medical and environmental applications of microorganisms

Current status and trends

Inhaltsverzeichnis

Kennzahlen

Kennzahlen