Stochastic economic modeling of the use of penethamate hydriodide (MamyzinÂ®) in heifers around calving to control peri-parturient mastitis

Mark A. Bryan; Gabriele M. Friton

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Stochastic economic modeling of the use of penethamate hydriodide (MamyzinÂ®) in heifers around calving to control peri-parturient mastitis

In: Mastitis in dairy production

Authors:

Mark A. Bryan

Mark A. Bryan

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Gabriele M. Friton

Gabriele M. Friton

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Type:: Chapter

Pages:: 232â234

DOI:: https://doi.org/10.3920/9789086865505_031

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In the spring of 2002 a prospective cohort study was carried out on the effect of the parenteral use of 10 g penethamate hydriodide (MamyzinÂ®) on heifers around calving to prevent mastitis within a commercial dairy herd in Central Southland, New Zealand.

Treated heifers showed a significant reduction in the incidence of mastitis (22.8% vs. 41.0%; RR = 0.52, p=0.029) after calving, and treatment was associated with an increased milk production (p=0.06 at first herd test after calving, corrected for days in milk). Cost benefit and sensitivity analysis using a deterministic model showed an overall return on investment (ROI) of NZ$186 per heifer, or 6.18 times the investment (based on NZ$30 treatment cost).

Using the key indicators derived from this model (daily production, expected mastitis incidence, milk and heifer value), a stochastic model was produced to determine the sensitivity of the ROI to different scenarios with varying herd size and production. The model showed that the ROI essentially varied between 4 and 10 and had a very close mean over a high number of iterations of around 7.2.

These data suggest that, presented with a group of heifers, with a high risk of pericalving mastitis, therapy at or around calving with MamyzinÂ® would likely be of significant preventative and economic benefit.

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Mastitis in dairy production

Current knowledge and future solutions

E-Book ISBN:: 9789086865505

Publisher:: Wageningen Academic

Print Publication Date:: 24 Oct 2005

Subjects
- Life Sciences

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Stochastic economic modeling of the use of penethamate hydriodide (MamyzinÂ®) in heifers around calving to control peri-parturient mastitis

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Mastitis in dairy production

Current knowledge and future solutions

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