Functional amino acids in swine nutrition and production

Guoyao Wu; Fuller W. Bazer; Robert C. Burghardt; Gregory A. Johnson; Sung Woo Kim; Darrell A. Knabe; Xilong Li; M. Carey Satterfield; Stephen B. Smith; Thomas E. Spencer

Functional amino acids in swine nutrition and production

In: Dynamics in animal nutrition

Authors:

Guoyao Wu

Guoyao Wu ¹Department of Animal Science, Texas A&M University, College Station, TX 77843, USA; g-wu@tamu.edu

Search for other papers by Guoyao Wu in
Current site
Google Scholar
PubMed

Fuller W. Bazer

Fuller W. Bazer ¹Department of Animal Science, Texas A&M University, College Station, TX 77843, USA; g-wu@tamu.edu

Search for other papers by Fuller W. Bazer in
Current site
Google Scholar
PubMed

Robert C. Burghardt

Robert C. Burghardt ²Department of Veterinary Integrative Bioscience, Texas A&M University, College Station, TX 77843, USA

Search for other papers by Robert C. Burghardt in
Current site
Google Scholar
PubMed

Gregory A. Johnson

Gregory A. Johnson ²Department of Veterinary Integrative Bioscience, Texas A&M University, College Station, TX 77843, USA

Search for other papers by Gregory A. Johnson in
Current site
Google Scholar
PubMed

Sung Woo Kim

Sung Woo Kim ³Department of Animal Science, North Carolina State University, Raleigh, NC 27695, USA

Search for other papers by Sung Woo Kim in
Current site
Google Scholar
PubMed

Darrell A. Knabe

Darrell A. Knabe ¹Department of Animal Science, Texas A&M University, College Station, TX 77843, USA; g-wu@tamu.edu

Search for other papers by Darrell A. Knabe in
Current site
Google Scholar
PubMed

Xilong Li

Xilong Li ¹Department of Animal Science, Texas A&M University, College Station, TX 77843, USA; g-wu@tamu.edu

Search for other papers by Xilong Li in
Current site
Google Scholar
PubMed

M. Carey Satterfield

M. Carey Satterfield ¹Department of Animal Science, Texas A&M University, College Station, TX 77843, USA; g-wu@tamu.edu

Search for other papers by M. Carey Satterfield in
Current site
Google Scholar
PubMed

Stephen B. Smith

Stephen B. Smith ¹Department of Animal Science, Texas A&M University, College Station, TX 77843, USA; g-wu@tamu.edu

Search for other papers by Stephen B. Smith in
Current site
Google Scholar
PubMed

, and

Thomas E. Spencer

Thomas E. Spencer ¹Department of Animal Science, Texas A&M University, College Station, TX 77843, USA; g-wu@tamu.edu

Search for other papers by Thomas E. Spencer in
Current site
Google Scholar
PubMed

Type:: Chapter

Pages:: 69–98

DOI:: https://doi.org/10.3920/9789086867066_006

Purchase instant access (PDF download and unlimited online access):

€42.00€35.00 excl. VAT

Add to Cart

Redeem Access Token

Amino acids were traditionally classified as nutritionally essential or nonessential for swine based on nitrogen balance and growth. It was also assumed without much evidence that pigs could synthesize sufficient amounts of all nonessential amino acids to support maximum production performance. Thus, over the past 50 years, much emphasis has been placed on the roles for dietary essential amino acids as building blocks for tissue proteins. Disappointingly, the current version of NRC does not recommend dietary requirements of so called ‘nonessential amino acids’ by neonatal, post-weaning, growing-finishing, or gestating pigs. However, a large body of literature shows that these nonessential amino acids, particularly glutamine and arginine, play important roles in regulating gene expression at both transcriptional and translational levels in animals. Additionally, both isotopic and digestive studies have established that large amounts of amino acids in the enteral diet are degraded by the small intestine during the first pass. Thus, only 5% of glutamate and aspartate, 30-33% of glutamine, and 60-65% of proline and arginine in the diet enter the portal circulation. Dynamic synthesis of amino acids via inter-organ metabolism depends on essential amino acids and may be suboptimal in pigs at various stages of the life cycle. Amino acids participate in cell signaling via mammalian target of rapamycin, AMP-activated protein kinase, extracellular signal-related kinase, Jun kinase, mitogen-activated protein kinase, and gases (NO, CO and H₂S). Exquisite integration of these regulatory networks has profound effects on cell proliferation, differentiation, metabolism, homeostasis, survival, and function. Importantly, recent advances in understanding of functional amino acids are transforming the practice of swine nutrition. Particularly, dietary supplementation

Citation Info

Save
Cite
Email this content

Share link with colleague or librarian

You can email a link to this page to a colleague or librarian:
Email this content
or copy the link directly:

https://brill.edhh.ma/abstract/book/9789086867066/BP000006.xml
The link was not copied. Your current browser may not support copying via this button.

Link copied successfully

Collapse
Expand

Dynamics in animal nutrition

E-Book ISBN:: 9789086867066

Publisher:: Wageningen Academic

Print Publication Date:: 15 Nov 2010

Subjects
- Life Sciences
  - General
  - Animal & Veterinary

Metrics

	All Time	Past 365 days	Past 30 Days
Abstract Views	770	221	40
Full Text Views	23	2	0
PDF Views & Downloads	30	8	0

African Studies	Education	Media Studies
American Studies	History	Middle East and Islamic Studies
Ancient Near East and Egypt	Human Rights and Humanitarian Law	Musicology
Art History	International Law	Philosophy
Asian Studies	International Relations	Religious Studies
Biblical Studies	Jewish Studies	Slavic and Eurasian Studies
Biology	Languages and Linguistics	Social Sciences
Book History and Cartography	Life Sciences	Theology and World Christianity
Classical Studies	Literature and Cultural Studies

Subjects

Authors

Open Access

Product Information

Company

Contact

Functional amino acids in swine nutrition and production

Citation Info

Share link with colleague or librarian

Dynamics in animal nutrition

Table of Contents

Metrics

Metrics