Save

Effects of Bifidobacterium longum BB536 on lipid profile and histopathological changes in hypercholesterolaemic rats

in Beneficial Microbes
Autor:innen:
S.H. Al-Sheraji Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
Department of Food Science, Faculty of Agriculture, Ibb University, Ibb, Yemen

Search for other papers by S.H. Al-Sheraji in
Current site
Google Scholar
PubMed
Close
,
I. Amin Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
Laboratory of Halal Science Research, Halal Products Research Institutes, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia

Search for other papers by I. Amin in
Current site
Google Scholar
PubMed
Close
,
A. Azlan Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
Laboratory of Halal Science Research, Halal Products Research Institutes, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia

Search for other papers by A. Azlan in
Current site
Google Scholar
PubMed
Close
,
M.Y. Manap Department of Food Technology, Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia

Search for other papers by M.Y. Manap in
Current site
Google Scholar
PubMed
Close
, und
F.A. Hassan Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
Department of Food Science, Faculty of Agriculture, Ibb University, Ibb, Yemen

Search for other papers by F.A. Hassan in
Current site
Google Scholar
PubMed
Close
Zitierung herunterladen Berechtigungen erhalten

Optionen für den Zugriff

Nutzen Sie bitte eine der untenstehenden Zugriffsmöglichkeiten, um den vollständigen Artikel zu lesen.

Institutszugang

Melden Sie sich mit Open Athens, Shibboleth oder Ihren institutionellen Anmeldedaten an.

Über Institut einloggen

Kauf

Sofortzugang erwerben (PDF-Download und unbegrenzter Online-Zugang):

36,93 €

Weitere Zugriffsmöglichkeiten

Auf DeepDyve mieten
Token einlösen

The present study investigated the effects of Bifidobacterium longum BB536 on lipid profile, liver and kidney function, and body fat in hypercholesterolaemic rats. 40 Sprague-Dawley rats were randomly divided into five groups. The negative control group received a standard diet. The positive control group received a cholesterol-enriched diet, whereas the intervention groups received a cholesterol-enriched diet supplemented with B. longum BB536 alone or in combination with inulin or Mangifera pajang fibrous polysaccharides. After 8 weeks, plasma lipids, and liver and kidney function were tested. Intake of the cholesterol-enriched diet increased total cholesterol, alanine aminotransferase, gamma-glutamyl transferase, creatinine, urea, liver weight, adipose tissue weight, liver lipid deposition and adipocyte size. B. longum BB536 supplementation significantly reduced total cholesterol, liver lipid deposition and adipocyte size, and positively affected liver and kidney function. These effects were significantly increased in the presence of inulin and M. pajang fibrous polysaccharides.

Kennzahlen

Insgesamt Letzte 365 Tage In den letzten 30 Tagen
Aufrufe von Kurzbeschreibungen 579 242 24
Gesamttextansichten 22 12 0
PDF-Downloads 22 19 0