Effects of Traditional Asian Diet on dietary fibre requirement, gut microbiome composition, and faecal and urine metabolomes in healthy Asian women: a pilot study
äºBeneficial MicrobesSchool of Health Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia
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MUM Microbiome Research Centre, Monash University Malaysia, Subang Jaya, Malaysia
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Abstract
The Traditional Asian Diet (TAD) is characterised by high dietary fibre and functional foods. This study investigated TADâs effects on meeting fibre requirements, gut microbiome, and faecal and urine metabolomes. A four-week randomised controlled trial was conducted among healthy Asian women allocated into the TAD group (n = 11) following a newly developed TAD program and the control group (n = 11). Assessments included dietary intake, gut health (symptoms, faecal form, frequency), serum fatty acids binding protein-2 (FABP-2) levels, faecal microbiome via 16s rRNA sequencing, and faecal and urine metabolites which were analysed using gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR), respectively. The TAD group showed significant increases in dietary fibre (
Clinical trial registration: NCT04885959, clinicaltrials.gov
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Effects of Traditional Asian Diet on dietary fibre requirement, gut microbiome composition, and faecal and urine metabolomes in healthy Asian women: a pilot study
äºBeneficial MicrobesSchool of Health Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia
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Abstract
The Traditional Asian Diet (TAD) is characterised by high dietary fibre and functional foods. This study investigated TADâs effects on meeting fibre requirements, gut microbiome, and faecal and urine metabolomes. A four-week randomised controlled trial was conducted among healthy Asian women allocated into the TAD group (n = 11) following a newly developed TAD program and the control group (n = 11). Assessments included dietary intake, gut health (symptoms, faecal form, frequency), serum fatty acids binding protein-2 (FABP-2) levels, faecal microbiome via 16s rRNA sequencing, and faecal and urine metabolites which were analysed using gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR), respectively. The TAD group showed significant increases in dietary fibre (
Clinical trial registration: NCT04885959, clinicaltrials.gov
| å ¨é¨æé´ | è¿å»ä¸å¹´ | è¿å»30天 | |
|---|---|---|---|
| æè¦æµè§æ¬¡æ° | 1320 | 791 | 32 |
| å ¨ææµè§æ¬¡æ° | 57 | 46 | 3 |
| PDFä¸è½½æ¬¡æ° | 118 | 95 | 3 |
