Reference system â Principle and practise

C. Baumgartner

Reference system â Principle and practise

In: Breeding, production recording, health and the evaluation of farm animals

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C. Baumgartner

C. Baumgartner Milchpruefring Bayern e.V., Hochstatt 2, 85283 Wolnzach, Germany

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Type:: Chapter

Pages:: 309

DOI:: https://doi.org/10.3920/9789086865932_054

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The definition of âreferenceâ covers two fields of meaning. One is dealing with âtestimonialâ, âendorsementâ or âcertificationâ; the other involves the aspect of âinformationâ, âevidenceâ or âsourceâ. These definitions describe very well the intentions of reference systems, which shall replace the traditional way of calibration of routine methods.

Traditionally linear calibration models are used, linking one routine analyzer via the characterisation of a calibration material to the reference method, carried out in a reference laboratory. This traditional scheme underlies some major restrictions: insufficient definition of the parameter to be measured, poor precision of reference methods compared to the precision data of routine methods, high variation between reference labs carrying out the reference methods, stability and homogeneity of characterized calibration materials (secondary reference materials - SRMs) and others.

But anyhow, due to the demands of a globalizing trade, analytical results should be comparable and equivalent worldwide, over time on the long run and between different analytical methods. This asks for more intelligent reference systems, using all information to control all sources of variation in the whole analytical process. Thus, feed back mechanisms can optimize and reduce the variation in carrying out reference methods as well as prove the validity of the SRMs used. Using the redundancy of the calibration data of routine analyzer clusters, much more information could be obtained about the quality of SRMs and their target values as well as the quality of routine calibrations.

To set up such a reference system a centralized data base has to be created to gather calibration data of routine analyzers. Of course a reporting system for routine labs is as crucial for the success as a reporting and cooperation system for the reference labs. As far as legally important and controlled parameters are concerned, also the competent authorities and scientists have to be part of such a reference system to assure an internationally accepted reference level for the respective parameter.

Up to now, the international structures to implement such a reference system are missing. ICAR should define its role and how to act to become a part of such international analytical reference systems.

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Breeding, production recording, health and the evaluation of farm animals

Series:Â EAAP Scientific Series, Volume: 121

E-Book ISBN:: 9789086865932

Publisher:: Wageningen Academic

Print Publication Date:: 01 Nov 2007

Subjects
- Life Sciences
  - General
  - Animal & Veterinary

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Reference system â Principle and practise

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Breeding, production recording, health and the evaluation of farm animals

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