Clinical Trials and the African Person aims to position the African notion of the self/person within the clinical trials context. As opposed to autonomy-based principlism, this other-regarding/communalist perspective is the preferred alternative model. This tactic draws further attention to the inadequacy of the principlist approach particularly in multicultural settings. It also engenders a rethink, stimulates interest, and re-assesses the failed assumptions of universal ethical principles.
As a novel attempt that runs against much of the prevailing (Euro-American) intellectual mood, this approach strives to introduce the African viewpoint by making explicit the import of the self in a re-contextualized arena, meaning within the community and a given milieu. Thus, research ethics must go beyond autonomy-based considerations for the individual, to rightly embed him/her within his/her community and the environment.
Ike V. Iyioke, Ph.D. (2015) Michigan State University, has backgrounds in philosophy, international relations, journalism, and teaching. He has taught healthcare ethics, business ethics, and African philosophy. A MacArthur Foundation/SSRC Fellow, his career has included print journalism and university administration.
Preface Acknowledgements List of Figures List of Abbreviations/Terms
Introduction
Part 1: Clinical Trials
1 Who is Responsible for Human Subjects (When Experiments Travel)?
â1.1âIntroduction
â1.2âExperimentation with Human Subjects: A Selective Rehash
ââ1.2.1âBurroughs Wellcome (Now GlaxoSmithKline) Experiments
ââ1.2.2âTuskegee Syphilis Study (1932â1972)
ââ1.2.3âNuremberg Experiments
ââ1.2.4âRadiation Experiments
ââ1.2.5âMustard gas Experiments
ââ1.2.6âThalidomide
ââ1.2.7âHenry Beecher Report
ââ1.2.8âJewish Chronic Disease Hospital and Willowbrook Tests
â1.3âEmergence of Research Ethics Codes
â1.4âOutsourcing of Clinical Trials
â1.5âTrovan Test Case
â1.6âConcluding Thoughts
2 Transgenic Mosquitoes Project as Model
â2.1âIntroduction
â2.2âSome Preliminaries
â2.3âThe GMM Model
â2.4âGMM Model and Biodiversity
â2.5âEnvironmental Ethics and Bioethics
â2.6âConcluding Thoughts
Part 2: Responsibility
3 Being Responsible
â3.1âIntroduction
â3.2âUnderstanding Responsibility
â3.3âResponsibility as a Virtue
â3.4âCorporate Responsibility
â3.5âConcluding Thoughts
Part 3: Personhood
4 Re-Conceiving Responsibility: A Role For Personhood in African Thought
â4.1âIntroduction
â4.2âThe âAfrican Manâ
â4.3âAfrican vs. Euro-American Personhood
â4.4âAfrican Personhood and Bioethics
â4.5âSummary
â4.6âThe Die is Cast
â4.7âConcluding Thoughts
â4.8âStudy Limitations/Directions for Future Studies
Bibiliography Index
All interested in cultural diversity in global bioethics, Africanists, biomedical scientists, scholars interested in formulating appropriate rubrics to shape discussions and promote African philosophical/multicultural values from this perspective.