Co-occurrence of mycotoxins, including aflatoxins, trichothecenes, and zearalenone, in Chinese feedstuffs collected in 2013 and 2014
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A total of 357 feedstuff samples, including cottonseed meal plus soybean meal (CSM), wheat bran (WB) and dried distillers grain with solubles (DDGS) collected from 14 provinces in China in 2013 and 2014 were analysed for the co-occurrence of mycotoxins, including 4 aflatoxins, 7 trichothecenes, and zearalenone (ZEA), by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS). Deoxynivalenol (DON) was the most prevalent mycotoxin found in Chinese feedstuffs, followed by ZEA and aflatoxin B1 (AFB1). It was found that out of 357 samples, 27 (7.6%), 11 (3.1%) and 5 (1.4%) samples were positive for DON, ZEA and AFB1 at levels exceeding the Chinese regulatory limit of 1000 μg/kg, 500 μg/kg, 50 μg/kg for DON, ZEA, and AFB1, respectively. DON, ZEA, and AFB1 levels ranged from 1,005.5 to 2,893.1 μg/kg, 510.8 to 4,845.9 μg/kg, and 53.9 to 72.9 μg/kg, respectively. These samples were more easily co-contaminated by other mycotoxins, such as DON, ZEA, AFB1, AFB2, 3-acetyldeoxynivalenol (3-ADON), and 15-ADON. CSM was more easily contaminated by aflatoxins than WB and DDGS, and WB was more easily contaminated by DON and ZEA. Besides, 339 samples (95.0%, 339/357) were contaminated by at least two mycotoxins, and 16 samples (4.5%, 16/357) were only contaminated by one mycotoxin, and 2 samples (0.6%, 2/357) were not contaminated by any mycotoxin studied. There were 30, 66, and 66 different mycotoxin combination types in CSM, WB, and DDGS, respectively, but DON+3-ADON+15- ADON+ZEA was the most frequent mycotoxin combination, with a frequency of 13.16% (5/38) in CSM, 17.29% (23/133) in WB, and 18.8% (35/186) in DDGS. These results indicate that mycotoxin co-occurrence is very common in Chinese feedstuffs, and it is very important to conduct multi-mycotoxin monitoring in Chinese feedstuffs.
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-
Berthiller, F., Sulyok, M., Krska, R. and Schumacher, R., 2007. Chromatographic methods for the simultaneous determination of mycotoxins and their conjugates in cereals. International Journal of Food Microbiology 119: 33-37.
'Chromatographic methods for the simultaneous determination of mycotoxins and their conjugates in cereals ' () 119 International Journal of Food Microbiology : 33 -37.
-
Bhat, R.V., Ramakrishna, Y., Beedu, S.R. and Munshi, K.L., 1989. Outbreak of trichothecene mycotoxicosis associated with consumption of mould-damaged wheat products in Kashmir Valley, India. The Lancet 333: 35-37.
'Outbreak of trichothecene mycotoxicosis associated with consumption of mould-damaged wheat products in Kashmir Valley, India ' () 333 The Lancet : 35 -37.
-
Binder, E.M., Tan, L.M., Chin, L.J., Handl, J. and Richard, J., 2007. Worldwide occurrence of mycotoxins in commodities feeds and feed ingredients. Animal Feed Science and Technology 137: 265-282.
'Worldwide occurrence of mycotoxins in commodities feeds and feed ingredients ' () 137 Animal Feed Science and Technology : 265 -282.
-
Biomin, 2014. Mycotoxin survey 2014. Available at:https://tinyurl.com/y8ndf9sb.
-
Borutova, R., Aragon, Y.A., Nährer, K. and Berthiller, F., 2012. Co-occurrence and statistical correlations between mycotoxins in feedstuffs collected in the Asia-Oceania in 2010. Animal Feed Science and Technology 178: 190-197.
'Co-occurrence and statistical correlations between mycotoxins in feedstuffs collected in the Asia-Oceania in 2010 ' () 178 Animal Feed Science and Technology : 190 -197.
-
Bryden, W.L., 2012. Mycotoxin contamination of the feed supply chain: implications for animal productivity and feed security. Animal Feed Science and Technology 173: 134-158.
'Mycotoxin contamination of the feed supply chain: implications for animal productivity and feed security ' () 173 Animal Feed Science and Technology : 134 -158.
-
Food and Agriculture Organization of the United Nations (FAO), 2004. Worldwide regulations for mycotoxins in food and feed in 2003. FAO, Rome, Italy. Available at:http://www.fao.org/docrep/007/y5499e/y5499e00.htm.
-
Gajecki, M., 2002. Zearalenone-undesirable substances in feed. Polish Journal of Veterinary Sciences 5: 117-122.
'Zearalenone-undesirable substances in feed ' () 5 Polish Journal of Veterinary Sciences : 117 -122.
-
Grenier, B. and Oswald, I.P., 2011. Mycotoxin co-contamination of food and feed: meta-analysis of publications describing toxicological interactions. World Mycotoxin Journal 4: 285-313.
'Mycotoxin co-contamination of food and feed: meta-analysis of publications describing toxicological interactions ' () 4 World Mycotoxin Journal : 285 -313.
-
Griessler, K., Rodrigues, I., Handl, J. and Hofstetter, U., 2010. Occurrence of mycotoxins in Southern Europe. World Mycotoxin Journal 3: 301-309.
'Occurrence of mycotoxins in Southern Europe ' () 3 World Mycotoxin Journal : 301 -309.
-
Huang, G.M., Li, X.H. and Duan, Z.Y., 2010. Analysis of mycotoxins contamination in feeds and raw materials. Swine Production 6: 6-8.
'Analysis of mycotoxins contamination in feeds and raw materials ' () 6 Swine Production : 6 -8.
-
Huang, G.M., Li, X.H., Yang, Y.L. and Lao, Y., 2014. Analysis of mycotoxins contamination in feeds and raw materials during 2012-2013. Swine Production 4: 17-18.
'Analysis of mycotoxins contamination in feeds and raw materials during 2012-2013 ' () 4 Swine Production : 17 -18.
-
Hussein, H.S. and Brasel, J.M., 2001. Toxicity, metabolism, and impact of mycotoxins on humans and animals. Toxicology 167: 101-134.
'Toxicity, metabolism, and impact of mycotoxins on humans and animals ' () 167 Toxicology : 101 -134.
-
Hygienical standard for feeds, 2017. GB 13078-2017. Available at:http://www.gb688.cn/bzgk/gb/ [In Chinese].
-
Ibáñez-Vea, M., Lizarraga, E., González-Peñas, E. and López de Cerain, A., 2012. Co-occurrence of type-A and type-B trichothecenes in barley from a northern region of Spain. Food Control 25: 81-88.
'Co-occurrence of type-A and type-B trichothecenes in barley from a northern region of Spain ' () 25 Food Control : 81 -88.
-
Ichinoe, M., Kurata, H., Sugiura, Y. and Ueno, Y., 1983. Chemotaxonomy ofGibberella zeae with special reference to production of trichothecenes and zearalenone. Applied and Environmental Microbiology 46: 1364-1369.
'Chemotaxonomy ofGibberella zeae with special reference to production of trichothecenes and zearalenone ' () 46 Applied and Environmental Microbiology : 1364 -1369.
-
Krska, R., Baumgartner, S. and Josephs, R., 2001. The state-of-the-art in the analysis of type-A and-B trichothecene mycotoxins in cereals. Fresenius Journal of Analytical Chemistry 371: 285-299.
'The state-of-the-art in the analysis of type-A and-B trichothecene mycotoxins in cereals ' () 371 Fresenius Journal of Analytical Chemistry : 285 -299.
-
Li, F.Q., Luo, X.Y. and Takumi, Y., 1999. Mycotoxins (trichothecenes, zearalenone and fumonisins) in cereals associated with human red-mold intoxications stored since 1989 and 1991 in China. Natural Toxins 7: 93-97.
'Mycotoxins (trichothecenes, zearalenone and fumonisins) in cereals associated with human red-mold intoxications stored since 1989 and 1991 in China ' () 7 Natural Toxins : 93 -97.
-
Liu, J., Sun, L.H., Zhang, J.C., Guo, J., Chen, L., Qi, D.S. and Zhang, N.Y., 2016. Aflatoxin B1, zearalenone and deoxynivalenol in feed ingredients and complete feed from central China. Food Additives and Contaminants Part B 9: 91-97.
'Aflatoxin B1, zearalenone and deoxynivalenol in feed ingredients and complete feed from central China ' () 9 Food Additives and Contaminants Part B : 91 -97.
-
Lopez-Garcia, R., Park, D.L. and Phillips, T.D., 1999. Integrated mycotoxin management systems. Preventing mycotoxin contamination. FAO, Rome, Italy, pp. 38-47.
'Integrated mycotoxin management systems ', in Preventing mycotoxin contamination , () 38 -47.
-
Peraica, M., Radic, B., Lucic, A. and Pavlovic, M., 1999. Toxic effects of mycotoxins in humans. Bulletin of the World Health Organisation 77: 754-766.
'Toxic effects of mycotoxins in humans ' () 77 Bulletin of the World Health Organisation : 754 -766.
-
Rodrigues, I., Handl, J. and Binder, E.M., 2010. Mycotoxin occurrence in commodities, feeds and feed ingredients sourced in the Middle East and Africa. Food Additives and Contaminants Part B 4: 168-179.
'Mycotoxin occurrence in commodities, feeds and feed ingredients sourced in the Middle East and Africa ' () 4 Food Additives and Contaminants Part B : 168 -179.
-
Speijers, G.J.A. and Speijers, M.H.M., 2004. Combined toxic effects of mycotoxins. Toxicology Letters 153: 91-98.
'Combined toxic effects of mycotoxins ' () 153 Toxicology Letters : 91 -98.
-
Streit, E., Schwab, C., Sulyok, M., Naehrer, K., Krska, R. and Schatzmayr, G., 2013. Multi-mycotoxin screening reveals the occurrence of 139 different secondary metabolites in feed and feed ingredients. Toxins 5: 504-523.
'Multi-mycotoxin screening reveals the occurrence of 139 different secondary metabolites in feed and feed ingredients ' () 5 Toxins : 504 -523.
-
Waseem, A., Shah, S.A., Sajjad, A., Siddiqi, A. and Nafees, M., 2014. Human exposure to mycotoxins: a retrospective review of leading toxins and metabolites in human biological matrices. Journal of the Chemical Society of Pakistan 36: 1196-1214.
'Human exposure to mycotoxins: a retrospective review of leading toxins and metabolites in human biological matrices ' () 36 Journal of the Chemical Society of Pakistan : 1196 -1214.
-
Yu, C.C., Sh., B. and Li, F.Q., 2010. Establishment of method for simultaneous detection of masked deoxynivalenol and other multi-mycotoxins in cereals. Chinese Journal of Integrative Medicine 44: 736-740.
'Establishment of method for simultaneous detection of masked deoxynivalenol and other multi-mycotoxins in cereals ' () 44 Chinese Journal of Integrative Medicine : 736 -740.
-
Zain, M.E., 2011. Impact of mycotoxins on humans and animals. Journal of Saudi Chemical Society 15: 129-144.
'Impact of mycotoxins on humans and animals ' () 15 Journal of Saudi Chemical Society : 129 -144.
Supplementary Materials
| å ¨é¨æé´ | è¿å»ä¸å¹´ | è¿å»30天 | |
|---|---|---|---|
| æè¦æµè§æ¬¡æ° | 359 | 168 | 23 |
| å ¨ææµè§æ¬¡æ° | 30 | 4 | 0 |
| PDFä¸è½½æ¬¡æ° | 17 | 0 | 0 |
Co-occurrence of mycotoxins, including aflatoxins, trichothecenes, and zearalenone, in Chinese feedstuffs collected in 2013 and 2014
äºWorld Mycotoxin JournalSearch for other papers by X. Han in
Current site
Google Scholar
PubMed
Search for other papers by W. Xu in
Current site
Google Scholar
PubMed
Search for other papers by F. Li in
Current site
Google Scholar
PubMed
Search for other papers by J. Xu in
Current site
Google Scholar
PubMed
A total of 357 feedstuff samples, including cottonseed meal plus soybean meal (CSM), wheat bran (WB) and dried distillers grain with solubles (DDGS) collected from 14 provinces in China in 2013 and 2014 were analysed for the co-occurrence of mycotoxins, including 4 aflatoxins, 7 trichothecenes, and zearalenone (ZEA), by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS). Deoxynivalenol (DON) was the most prevalent mycotoxin found in Chinese feedstuffs, followed by ZEA and aflatoxin B1 (AFB1). It was found that out of 357 samples, 27 (7.6%), 11 (3.1%) and 5 (1.4%) samples were positive for DON, ZEA and AFB1 at levels exceeding the Chinese regulatory limit of 1000 μg/kg, 500 μg/kg, 50 μg/kg for DON, ZEA, and AFB1, respectively. DON, ZEA, and AFB1 levels ranged from 1,005.5 to 2,893.1 μg/kg, 510.8 to 4,845.9 μg/kg, and 53.9 to 72.9 μg/kg, respectively. These samples were more easily co-contaminated by other mycotoxins, such as DON, ZEA, AFB1, AFB2, 3-acetyldeoxynivalenol (3-ADON), and 15-ADON. CSM was more easily contaminated by aflatoxins than WB and DDGS, and WB was more easily contaminated by DON and ZEA. Besides, 339 samples (95.0%, 339/357) were contaminated by at least two mycotoxins, and 16 samples (4.5%, 16/357) were only contaminated by one mycotoxin, and 2 samples (0.6%, 2/357) were not contaminated by any mycotoxin studied. There were 30, 66, and 66 different mycotoxin combination types in CSM, WB, and DDGS, respectively, but DON+3-ADON+15- ADON+ZEA was the most frequent mycotoxin combination, with a frequency of 13.16% (5/38) in CSM, 17.29% (23/133) in WB, and 18.8% (35/186) in DDGS. These results indicate that mycotoxin co-occurrence is very common in Chinese feedstuffs, and it is very important to conduct multi-mycotoxin monitoring in Chinese feedstuffs.
| å ¨é¨æé´ | è¿å»ä¸å¹´ | è¿å»30天 | |
|---|---|---|---|
| æè¦æµè§æ¬¡æ° | 359 | 168 | 23 |
| å ¨ææµè§æ¬¡æ° | 30 | 4 | 0 |
| PDFä¸è½½æ¬¡æ° | 17 | 0 | 0 |
