Save

5-AMINOLEVULINATE SYNTHASE IS PRESENT, BUT PORPHYRINS DO NOT ACCUMULATE, IN THE HARDERIAN GLANDS OF THE MOLE RAT, SPALAX EHRENBERGI, AND TWO SPECIES OF SPINY MICE, ACOMYS CAHIRINUS AND A. RUSSATUS

In: Israel Journal of Ecology and Evolution
Authors:
ABRAHAM HAIM Department of Biology, University of Haifa at Oranim

Search for other papers by ABRAHAM HAIM in
Current site
Google Scholar
PubMed
Close
,
URI SHANAS Department of Zoology, University of Tel Aviv

Search for other papers by URI SHANAS in
Current site
Google Scholar
PubMed
Close
,
KIRSTEN M. OATES Department of Anatomy and Cell Biology, University of Alberta

Search for other papers by KIRSTEN M. OATES in
Current site
Google Scholar
PubMed
Close
,
CLIFFORD B SAMPLE Department of Anatomy and Cell Biology, University of Alberta

Search for other papers by CLIFFORD B SAMPLE in
Current site
Google Scholar
PubMed
Close
, and
GERALD R. BUZZELL Department of Anatomy and Cell Biology, University of Alberta

Search for other papers by GERALD R. BUZZELL in
Current site
Google Scholar
PubMed
Close
Download Citation Get Permissions

Access options

Get access to the full article by using one of the access options below.

Institutional Login

Log in with Open Athens, Shibboleth, or your institutional credentials

Login via Institution

Purchase

Buy instant access (PDF download and unlimited online access):

€36.93

We have examined porphyrins and 5-aminolevulinate synthase (ALAS), the rate-limiting enzyme of porphyrin synthesis, in Harderian glands from the mole rat (Spalax ehrenbergi) and two species of spiny mice of the genus Acomys. In both groups of rodents, the Harderian glands lacked measurable porphyrins. However, Western blots probed with an antibody showed appreciable concentrations of ALAS protein. If ALAS protein represents the active enzyme, these results suggest that porphyrins are produced in these animals but are rapidly metabolized.

Content Metrics

All Time Past 365 days Past 30 Days
Abstract Views 142 54 12
Full Text Views 11 0 0
PDF Views & Downloads 6 0 0