THE EFFECT OF STARVATION AND VITAMIN B6 DEFICIENCY ON GONADOTROPHIN-STIMULATED GLUTAMIC-OXALACETIC TRANSAMINASE
äºIsrael Journal of Ecology and EvolutionSearch for other papers by B. ECKSTEIN in
Current site
Google Scholar
Search for other papers by Z. PASTER in
Current site
Google Scholar
A distinction between vitamin B6 deficiency and inanition was shown by the determination of glutamic-oxalacetic transaminase (GOT) activity in the ovary and uterus of noninjected and gonadotrophin treated rats. While in the ovaries of vitamin B6 deficient rats the GOT activity is reduced to half of the normal, in the ovaries of starved rats the enzyme level is the same as in fed rats. Gonadotrophin administration causes a marked GOT elevation in both fed and starved rats, while in the vitamin B6 deficient rats no elevation in enzyme activity was found.
On the basis of these results it is concluded that a distinction has to be drawn between effects of inanition associated with a vitamin deficiency, and the specific vitamin effect.
Purchase
Buy instant access (PDF download and unlimited online access):
Institutional Login
Log in with Open Athens, Shibboleth, or your institutional credentials
Personal login
Log in with your brill.com account
-
Blivais B.B., Hanson R.O., Rosenzweig R.E., Mcneil KSexual development in female rats treated with Cortison Proc. Soc. exper. Biol. Med 1954 86 678
-
Drill V.A., Burrill M.W.Effect of thiamine deficiency and controlled inanition on ovarian function Endocrinology 1944 35 187
-
Drill V.A., Pfeiffer C.A.Effect of vitamin B complex deficiency, controlled inanition and methionine on inactivation of estrogen by the liver Endocrinology 1946 38 300
-
Eckstein B.Glutamic oxalacetic transaminase activity in the ovary of hypothyroid and vitamin B6 deficient rats Endocrinology 1963 72 777
-
Eckstein B., Shain H.The development of the ovary of the rat III. The effect of gonadotropins on glutamic-oxalacetic transaminase Acta Endocrinologica 1963 42 389
-
Ershoff B.H.Nutrition and anterior pituitary with special references to the general adaptation syndrome Vitamins and Hormones 1952 10 79
-
Evans H.M., Bishop K.S.Production of sterility with nutritional regimes adequate for growth and its cure with other foodstufss Jour. met. Res 1923 3 233
-
Greep R.O., Physiology of the Anterior Hypophysis in relation to Reproduction, in Sex and Internal Secretion Young W.C.William and Wilkins Co. 1961 I. 240
-
Maddock W.O., Heller C.G.Dichotomy between hypophysial content and amount of circulating gonadotropins dining starvation Proc. Soc. Exp. Biol. Med 1947 66 595
-
Marrian G.F., Parkes A.S.The effect of anterior pituitary preparation administered during dietary anoestrus Proc. Roy. Soc. London, ser. B 1929 105 248
-
Meites J.Relation of nutrition to endocrine reproductive function Iowa State Coll. J. Sc 1953 28 19
-
Meites J., Reed J.O.Effects of restricted feed intake in intact and ovariectomized rats on pituitary lactogen and gonadotropin Proc, Soc. Exper. Biol. Med 1949 70 513
-
Mulinos M.G., Pomerantz L.Pesudo-hypophysectomy, condition resembling hypophysectomy produced by malnutrition J. Nutrition 1940 19 493
-
Parkes A.S.Nature of anoestrous condition resulting from vitamin B deficiency Quart. J. Exp. Physiol 1928 18 397
-
Pearse A.G., Rinaldini L.M.Histochemical determination of gonadotropin in the rat hypophysis Brit. J. Exper. Pathol 1950 31 540
-
Pomerantz L., Mulinos M.G.Pseudohypophysectomy produced by inanition Am. J. Physiol 1939 126 601
-
Rinaldini L.M.Effect of chronic inamtion on the gonadotropic content of the pituitary gland J. Endocrinol 1949 6 54
-
Segaloff A., Segaloff A.The role of the vitamins of the B complex in estrogen metabolism Endocrinology 1944 34 346
-
Skelton F.R.Some specific and non specific effects of thiamine deficiency in the rat Proc. Soc. Exp. biol. Med 1950 73 516
-
Tonhazy N.E., White N.G., Umbreit W.W.Rapid method for estimation of glutamic-aspartic transaminase in tissues and its application to radiation sickness Arch. Biochem 1950 28 36
-
Vanderlinde R.E., Westerfeld W.W.The inactivation of estrone in rats in relation to dietary effects on liver Endocrinology 1950 47 265
-
Werner S.C.Failure of the gonadotropic function of the rat hypophysis during chronic inanition Proc. Soc. Exp. Biol. Med 1939 41 101
-
Wooten E., Nelson M.M., Simpson M.E., Evans H.M.Effect of pyridoxine deficiency on the gonadotrophic content of the anterior pituitary of the rat Endocrinology 1955 56 59
-
Wooten E., Nelson M.M., Simpson M.E., Evans H.M.Response of vitamin B6-deficient rats to hypophysial follicle stimulating and interstitial cell-stimulating hormones Endocrinology 1958 63 860
| å ¨é¨æé´ | è¿å»ä¸å¹´ | è¿å»30天 | |
|---|---|---|---|
| æè¦æµè§æ¬¡æ° | 108 | 31 | 8 |
| å ¨ææµè§æ¬¡æ° | 12 | 0 | 0 |
| PDFä¸è½½æ¬¡æ° | 13 | 0 | 0 |
THE EFFECT OF STARVATION AND VITAMIN B6 DEFICIENCY ON GONADOTROPHIN-STIMULATED GLUTAMIC-OXALACETIC TRANSAMINASE
äºIsrael Journal of Ecology and EvolutionSearch for other papers by B. ECKSTEIN in
Current site
Google Scholar
PubMed
Search for other papers by Z. PASTER in
Current site
Google Scholar
PubMed
A distinction between vitamin B6 deficiency and inanition was shown by the determination of glutamic-oxalacetic transaminase (GOT) activity in the ovary and uterus of noninjected and gonadotrophin treated rats. While in the ovaries of vitamin B6 deficient rats the GOT activity is reduced to half of the normal, in the ovaries of starved rats the enzyme level is the same as in fed rats. Gonadotrophin administration causes a marked GOT elevation in both fed and starved rats, while in the vitamin B6 deficient rats no elevation in enzyme activity was found.
On the basis of these results it is concluded that a distinction has to be drawn between effects of inanition associated with a vitamin deficiency, and the specific vitamin effect.
| å ¨é¨æé´ | è¿å»ä¸å¹´ | è¿å»30天 | |
|---|---|---|---|
| æè¦æµè§æ¬¡æ° | 108 | 31 | 8 |
| å ¨ææµè§æ¬¡æ° | 12 | 0 | 0 |
| PDFä¸è½½æ¬¡æ° | 13 | 0 | 0 |
