Resistance exercise (RE) imposes stress on the heart, as evidenced by single-set of RE protocols. N-acetylcysteine (NAC) is a supplement previously shown to reduce fatigue and improve cardiovascular function. This study aimed to examine the acute effect of oral NAC administration on cardiac stress during whole body regular RE. Nine recreationally strength-trained college students completed this randomised, double-blind, placebo-controlled crossover study. Each participant completed two sessions with one week apart, receiving either NAC (1,800 mg) or placebo (PLA) one hour prior to exercise. The RE protocol consisted of six exercises: leg extension (LE), seated chest press (SCP), leg curl (LC), seated row (SR), seated shoulder press (SSP), and lat pull-down (LPD). Participants performed 3 sets of 10 repetitions at 80% of one-repetition maximum (1RM) with two minutes rest between sets and exercises. Heart rate (HR) and blood pressure (BP) were measured at baseline and immediately after each set. Rate pressure product (RPP), an index of cardiac stress, was calculated from HR and systolic BP (SBP). Repeated measures ANOVA were used to compare RPP across interventions and exercises, with statistical significance set at
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Resistance exercise (RE) imposes stress on the heart, as evidenced by single-set of RE protocols. N-acetylcysteine (NAC) is a supplement previously shown to reduce fatigue and improve cardiovascular function. This study aimed to examine the acute effect of oral NAC administration on cardiac stress during whole body regular RE. Nine recreationally strength-trained college students completed this randomised, double-blind, placebo-controlled crossover study. Each participant completed two sessions with one week apart, receiving either NAC (1,800 mg) or placebo (PLA) one hour prior to exercise. The RE protocol consisted of six exercises: leg extension (LE), seated chest press (SCP), leg curl (LC), seated row (SR), seated shoulder press (SSP), and lat pull-down (LPD). Participants performed 3 sets of 10 repetitions at 80% of one-repetition maximum (1RM) with two minutes rest between sets and exercises. Heart rate (HR) and blood pressure (BP) were measured at baseline and immediately after each set. Rate pressure product (RPP), an index of cardiac stress, was calculated from HR and systolic BP (SBP). Repeated measures ANOVA were used to compare RPP across interventions and exercises, with statistical significance set at
| All Time | Past 365 days | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 276 | 276 | 9 |
| Full Text Views | 2 | 2 | 0 |
| PDF Views & Downloads | 7 | 7 | 0 |