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Changes in serum irisin, PGC-1α, and IL-6 following combined strength-endurance training in obese young women
in Comparative Exercise PhysiologySport and Exercise Research Center, Universitas Negeri Surabaya, Surabaya, Indonesia
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Abstract
Obesity is characterised by excessive body fat accumulation, leading to an imbalance in myokine secretion, contributing to increased low-grade chronic inflammation. Therefore, strategies to reduce fat accumulation and control inflammation are essential in obesity management. This study aims to investigate the changes in serum irisin, peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1α), and interleukin (IL)-6 induced by combined strength-endurance training in obese young adult women. A total of 24 obese women aged 20-25 years, with a body fat percentage of â¥30%, were recruited and randomly assigned to either a strength-endurance training group (n = 12) or a control group (n = 12). Only the training group underwent an eight-week strength-endurance intervention. Enzyme-linked immunosorbent assay (ELISA) was used to analyse serum concentrations of irisin, PGC-1α, and IL-6 in all samples. Statistical analysis using an mixed-model ANOVA with a significance level of 5% and effect size analysis using Cohenâs d. Significant differences were observed between the control and training groups in post-irisin (Effect size (ES): 2.283), Î-irisin (ES: 2.031), post-PGC-1α (ES: 1.571), Î-PGC-1α (ES: 1.155), post-IL-6 (ES: 0.955), and Î-IL-6 (ES: 1.438) (all
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Changes in serum irisin, PGC-1α, and IL-6 following combined strength-endurance training in obese young women
in Comparative Exercise PhysiologySport and Exercise Research Center, Universitas Negeri Surabaya, Surabaya, Indonesia
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Abstract
Obesity is characterised by excessive body fat accumulation, leading to an imbalance in myokine secretion, contributing to increased low-grade chronic inflammation. Therefore, strategies to reduce fat accumulation and control inflammation are essential in obesity management. This study aims to investigate the changes in serum irisin, peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1α), and interleukin (IL)-6 induced by combined strength-endurance training in obese young adult women. A total of 24 obese women aged 20-25 years, with a body fat percentage of â¥30%, were recruited and randomly assigned to either a strength-endurance training group (n = 12) or a control group (n = 12). Only the training group underwent an eight-week strength-endurance intervention. Enzyme-linked immunosorbent assay (ELISA) was used to analyse serum concentrations of irisin, PGC-1α, and IL-6 in all samples. Statistical analysis using an mixed-model ANOVA with a significance level of 5% and effect size analysis using Cohenâs d. Significant differences were observed between the control and training groups in post-irisin (Effect size (ES): 2.283), Î-irisin (ES: 2.031), post-PGC-1α (ES: 1.571), Î-PGC-1α (ES: 1.155), post-IL-6 (ES: 0.955), and Î-IL-6 (ES: 1.438) (all
| Insgesamt | Letzte 365 Tage | In den letzten 30 Tagen | |
|---|---|---|---|
| Aufrufe von Kurzbeschreibungen | 429 | 429 | 19 |
| Gesamttextansichten | 14 | 14 | 0 |
| PDF-Downloads | 88 | 88 | 0 |
