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Effects of resistance training combined with creatine hydrochloride or creatine monohydrate supplementation on oxidative stress-antioxidant markers in trained women: a double-blind randomized placebo-controlled trial
in Comparative Exercise PhysiologySearch for other papers by S.S. Dadvand in
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Department of Exercise Physiology, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran
Search for other papers by H. Arazi in
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Abstract
This study evaluated the effects of resistance training (RT) combined with creatine hydrochloride (CrHCL) and creatine monohydrate (CrM) supplementation on oxidative stress-antioxidant markers in trained women. In this study, 48 young trained women were selected and randomly assigned to four groups via a double-blind method: Group 1: RT + Creatine hydrochloride (Cr-HCL) supplementation (n = 12), Group 2: RT + Creatine monohydrate-loading phase (CrM-LP) supplementation (n = 12), Group 3: RT + CrM-without loading phase (CrM-WLP) supplementation (n = 12), and Group 4: RT + Placebo (PL) supplementation (n = 12). The RT program was performed for eight weeks with three sessions per week. Blood samples were obtained before and after training to evaluate serum levels of 8-hydroxy-2-deoxyguanosine (8-OHdG), malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPX) and catalase (CAT) activity. Statistical analyses were performed using the Mixed ANOVA and Bonferroni post-hoc tests at a significance level of 0.05. Following the intervention, the RT + Cr-HCL, RT + CrM-LP, and RT + CrM-WLP supplementation groups indicated significant decreases and increases in the blood levels of MDA and SOD, respectively, compared to the RT + PL supplementation group (
The study was conducted based on the Declaration of Helsinki and was approved by the ethics committee of the Sport Sciences Research Institute (IR.SSRC.REC.1399.138).
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Effects of resistance training combined with creatine hydrochloride or creatine monohydrate supplementation on oxidative stress-antioxidant markers in trained women: a double-blind randomized placebo-controlled trial
in Comparative Exercise PhysiologySearch for other papers by S.S. Dadvand in
Current site
Google Scholar
PubMed
Department of Exercise Physiology, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran
Search for other papers by H. Arazi in
Current site
Google Scholar
PubMed
Abstract
This study evaluated the effects of resistance training (RT) combined with creatine hydrochloride (CrHCL) and creatine monohydrate (CrM) supplementation on oxidative stress-antioxidant markers in trained women. In this study, 48 young trained women were selected and randomly assigned to four groups via a double-blind method: Group 1: RT + Creatine hydrochloride (Cr-HCL) supplementation (n = 12), Group 2: RT + Creatine monohydrate-loading phase (CrM-LP) supplementation (n = 12), Group 3: RT + CrM-without loading phase (CrM-WLP) supplementation (n = 12), and Group 4: RT + Placebo (PL) supplementation (n = 12). The RT program was performed for eight weeks with three sessions per week. Blood samples were obtained before and after training to evaluate serum levels of 8-hydroxy-2-deoxyguanosine (8-OHdG), malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPX) and catalase (CAT) activity. Statistical analyses were performed using the Mixed ANOVA and Bonferroni post-hoc tests at a significance level of 0.05. Following the intervention, the RT + Cr-HCL, RT + CrM-LP, and RT + CrM-WLP supplementation groups indicated significant decreases and increases in the blood levels of MDA and SOD, respectively, compared to the RT + PL supplementation group (
The study was conducted based on the Declaration of Helsinki and was approved by the ethics committee of the Sport Sciences Research Institute (IR.SSRC.REC.1399.138).
| Insgesamt | Letzte 365 Tage | In den letzten 30 Tagen | |
|---|---|---|---|
| Aufrufe von Kurzbeschreibungen | 786 | 605 | 33 |
| Gesamttextansichten | 34 | 30 | 1 |
| PDF-Downloads | 60 | 51 | 2 |
