The pattern of hippocampal neuronal, LTP and unilateral labyrinthectomy in male rats: the role of exercise and curcumin
äºComparative Exercise PhysiologySearch for other papers by N. Khalaji in
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Department of Anatomical Sciences, Faculty of Medicine, Urmia University of Medical Sciences, 5715799313 Urmia, Iran.
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A wide range of cognitive disorders, long-term potentiation (LTP) disorders, and biochemical changes have been reported in labyrinthectomy situations in the hippocampus of rodents. In order to investigate whether exercise and/or curcumin induce LTP and increase neurons in the hippocampus of unilateral labyrinthectomy male rats, after undergoing labyrinthectomy, animals were subjected to treadmill exercises after the intraperitoneal injection of curcumin five days per week, for 30 days. An increase of LTP and neuron count of the hippocampus was observed in unilateral labyrinthectomy rats. Interestingly the combination of exercise and curcumin did not enhance LTP in unilateral labyrinthectomy rats. These findings demonstrated that treadmill exercise and curcumin individually, significantly affect reinforcement of many of the pathological processes playing a role in increasing memory in unilateral labyrinthectomy situations.
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Supplementary Materials
| å ¨é¨æé´ | è¿å»ä¸å¹´ | è¿å»30天 | |
|---|---|---|---|
| æè¦æµè§æ¬¡æ° | 275 | 86 | 18 |
| å ¨ææµè§æ¬¡æ° | 11 | 0 | 0 |
| PDFä¸è½½æ¬¡æ° | 11 | 1 | 0 |
The pattern of hippocampal neuronal, LTP and unilateral labyrinthectomy in male rats: the role of exercise and curcumin
äºComparative Exercise PhysiologySearch for other papers by N. Khalaji in
Current site
Google Scholar
PubMed
Search for other papers by G. Aminpour in
Current site
Google Scholar
PubMed
Department of Anatomical Sciences, Faculty of Medicine, Urmia University of Medical Sciences, 5715799313 Urmia, Iran.
Search for other papers by B. Pourheydar in
Current site
Google Scholar
PubMed
Search for other papers by N. Abdollahzade in
Current site
Google Scholar
PubMed
Search for other papers by H. Parsaie in
Current site
Google Scholar
PubMed
Search for other papers by L. Derafshpour in
Current site
Google Scholar
PubMed
A wide range of cognitive disorders, long-term potentiation (LTP) disorders, and biochemical changes have been reported in labyrinthectomy situations in the hippocampus of rodents. In order to investigate whether exercise and/or curcumin induce LTP and increase neurons in the hippocampus of unilateral labyrinthectomy male rats, after undergoing labyrinthectomy, animals were subjected to treadmill exercises after the intraperitoneal injection of curcumin five days per week, for 30 days. An increase of LTP and neuron count of the hippocampus was observed in unilateral labyrinthectomy rats. Interestingly the combination of exercise and curcumin did not enhance LTP in unilateral labyrinthectomy rats. These findings demonstrated that treadmill exercise and curcumin individually, significantly affect reinforcement of many of the pathological processes playing a role in increasing memory in unilateral labyrinthectomy situations.
| å ¨é¨æé´ | è¿å»ä¸å¹´ | è¿å»30天 | |
|---|---|---|---|
| æè¦æµè§æ¬¡æ° | 275 | 86 | 18 |
| å ¨ææµè§æ¬¡æ° | 11 | 0 | 0 |
| PDFä¸è½½æ¬¡æ° | 11 | 1 | 0 |
