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Biomonitoring aflatoxin B1 exposure of residents from the Amazon region: a pilot study
in World Mycotoxin JournalSearch for other papers by K.M. Higashioka in
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Search for other papers by A.M. Kluczkovski in
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Search for other papers by A.C.S. Lucas in
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The present study was a pilot study that aimed to evaluate the occurrence of aflatoxins (AF) in the human diets and its presence in human urine as a metabolite (aflatoxin M1; AFM1). Volunteers from the Amazon region were evaluated before and after the consumption of 2 Brazil nuts/day for thirty days. At the end of 30 days (t=30) without the consumption of Brazil nuts, 9 samples (30%) were positive for AFM1. After 30 days (t=30) consuming 2 Brazil nuts per day, there was a reduction to 2 positive samples (7%). Questionnaires were also applied to volunteers, and the foods most often cited as consumed in their normal diet were cereals and bovine milk. However, there was no statistical relationship between these foods and the levels of AFM1 in the urine or in relation to those who already consumed Brazil nuts in culinary preparations or derived products. Despite the reduction of positive samples for AFM1 after 30 days of Brazil nut consumption, we suggest further studies regarding the clinical condition and genetics of individuals from the Amazon region, as well as the nutrient levels of the diet, e.g. for selenium, and which may protect the human body against aflatoxins.
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| Insgesamt | Letzte 365 Tage | In den letzten 30 Tagen | |
|---|---|---|---|
| Aufrufe von Kurzbeschreibungen | 253 | 96 | 9 |
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Biomonitoring aflatoxin B1 exposure of residents from the Amazon region: a pilot study
in World Mycotoxin JournalSearch for other papers by K.M. Higashioka in
Current site
Google Scholar
PubMed
Search for other papers by A.M. Kluczkovski in
Current site
Google Scholar
PubMed
Search for other papers by E.S. Lima in
Current site
Google Scholar
PubMed
Search for other papers by A.C.S. Lucas in
Current site
Google Scholar
PubMed
The present study was a pilot study that aimed to evaluate the occurrence of aflatoxins (AF) in the human diets and its presence in human urine as a metabolite (aflatoxin M1; AFM1). Volunteers from the Amazon region were evaluated before and after the consumption of 2 Brazil nuts/day for thirty days. At the end of 30 days (t=30) without the consumption of Brazil nuts, 9 samples (30%) were positive for AFM1. After 30 days (t=30) consuming 2 Brazil nuts per day, there was a reduction to 2 positive samples (7%). Questionnaires were also applied to volunteers, and the foods most often cited as consumed in their normal diet were cereals and bovine milk. However, there was no statistical relationship between these foods and the levels of AFM1 in the urine or in relation to those who already consumed Brazil nuts in culinary preparations or derived products. Despite the reduction of positive samples for AFM1 after 30 days of Brazil nut consumption, we suggest further studies regarding the clinical condition and genetics of individuals from the Amazon region, as well as the nutrient levels of the diet, e.g. for selenium, and which may protect the human body against aflatoxins.
| Insgesamt | Letzte 365 Tage | In den letzten 30 Tagen | |
|---|---|---|---|
| Aufrufe von Kurzbeschreibungen | 253 | 96 | 9 |
| Gesamttextansichten | 7 | 0 | 0 |
| PDF-Downloads | 10 | 0 | 0 |
