Möchten Sie über diese Zeitschrift informiert bleiben? Klicken Sie bitte auf die Buttons, um unsere Alerts zu abonnieren.
Möchten Sie über diese Zeitschrift informiert bleiben? Klicken Sie bitte auf die Buttons, um unsere Alerts zu abonnieren.
FETAL OXYGEN SUPPLY AND DEMAND: COMPARATIVE ASPECTS
in Israel Journal of Ecology and EvolutionSearch for other papers by GIACOMO MESCHIA in
Current site
Google Scholar
Experimental evidence in six placental mammals (horse, cattle, sheep, man, rhesus monkey, and guinea pig) indicates that fetal O2 uptake per unit fetal body mass does not vary markedly from small to large animals, in sharp contrast to the fact that small adults have a much greater O2 consumption rate per unit body mass than large adults. As a consequence, in an 800-g guinea pig, the mass-specific O2 consumption of the pregnant uterus is less than the mass-specific O2 consumption of the maternal organism, whereas the opposite is true in a 50-kg sheep. This effect of body size on the relationship between maternal and uterine O2 consumption may provide a physiological explanation for the evidence that small mammals are capable of producing a greater total newborn mass in relation to maternal body mass than large mammals.
There are major differences among pregnant mammals in the rate of uterine perfusion which is used to supply O2 to the fetus. Variability in placental structure accounts in part for these differences. In a countercurrent exchange placenta, uterine perfusion can be much smaller than in a venous equilibration exchange placenta and yet provide the same level of fetal oxygenation.
Kauf
Sofortzugang erwerben (PDF-Download und unbegrenzter Online-Zugang):
Institutszugang
Melden Sie sich mit Open Athens, Shibboleth oder Ihren institutionellen Anmeldedaten an.
Persönliche Anmeldung
Melden Sie sich mit Ihrem brill.com-Konto an
-
Abrams R.M., Caton D., Cotter J.R., Barron D.H.The oxygen consumption of the uterus and its tissue contents in late gestation: A comparison of simultaneous measurements using two different techniques Q. J. Exp. Physiol 1972 57 24 29
-
Battaglia F.C., Meschia G.In: An Introduction to Fetal Physiology Academic Press OrlandoFL 1986 179
-
Behrman R.E., Lees M.H., Peterson E.N., DeLannoy C.W., Seeds A.E.Distribution of the circulation in the normal and asphyxiated fetal primate Am. J. Obstet. Gynecol 1970 108 956 969
-
Bell A.W., Battaglia F.C., Meschia G.Relation between metabolic rate and body size in the ovine fetus J. Nutr 1987 117 1181 1186
-
Comline R.S., Silver M.Some aspects of foetal and utero-placental metabolism in cows with indwelling umbilical and uterine vascular catheters J. Physiol 1976 260 571 586
-
Faber J., Hart F.M.The rabbit placenta as an organ of diffusional exchange Circ. Res 1966 19 816
-
Günther B.Dimensional analysis and theory of biological similarity Physiol. Rev 1975 55 659 699
-
Hohimer A.R., Morton M.J., Metcalfe J.Maternal hemodynamics during guinea pig pregnancy Physiologist 1980 23 4148 (Abstract)
-
Johnson R.L., Gilbert M., Meschia G., Battaglia F.C.Cardiac output distribution and uteroplacental blood flow in the pregnant rabbit: A comparative study Am. J. Obstet. Gynecol 1985 151 682 686
-
Kleiber M., Respiratory exchange and metabolic rate. Handbook of physiology respiration Fenn W.O., Rahn H.American Physiological Society Bethesda 1965 2 927 938MD, Vol., Chapter 35
-
Leitch I., Hytten F.E., Billewicz W.Z.The maternal and neonatal weights of some mammals Proc. Zool. Soc. (London) 1959 133 11 28
-
Meier P.R., Manchester D.K., Battaglia F.C., Meschia G.Fetal heart rate in relation to body mass Proc. Soc. Exp. Biol. Med 1983 172 107 110
-
Meschia G., Placental respiratory gas exchange and fetal oxygenation. Maternal-fetal medicine, principles and practice Creasy R.K., Resnik R.W.B. Saunders PhiladelphiaPA 1994 288 297Chapter 19
-
Moll W., Künzel W., Ross H.G.Gas exchange of the pregnant uterus of anesthetized and unanesthetized guinea pig Respir. Physiol 1970 8 303 318
-
Mossman H.The rabbit placenta and the problem of placental transmission Am. J. Anat 1926 37 433
-
Murray R.D., Jones R.O., Johnson R., Meschia G., Battaglia F.C.Uterine and whole body oxygen extractions in the pregnant rabbit under chronic steady state conditions Am. J. Obstet. Gynecol 1985 152 709 715
-
Myers S.A., Sparks J.W., Makowski E.L., Meschia G., Battaglia F.C.Relationship between placental blood flow and placental and fetal size in guinea pig Am. J. Physiol 1982 243H404
-
Peeters L.L., Gratters G., Martin C.B.Distribution of cardiac output in the unstressed pregnant guinea pig. Society Gynecological Investigation 27th Annu. Mtg., Denver, CO, p.38. (Abstract) 1980
-
Rosenfeld C.R.Distribution of cardiac output in ovine pregnancy. Am. J. Physiol. 232 (Heart Circ. Physiol. 1): H231–H235 1977
-
Sandiford I., Wheeler T.The basal metabolism before, during and after pregnancy J. Biol. Chem 1924 62 329 350
-
Shield J.Oxygen consumption during pouch development of the macropod marsupial setanix brachyurus J. Physiol. (London) 1966 187 257 270
-
Silver M., Comline R.S., Fetal and placental 02 consumption and the uptake of different metabolites in the ruminant and horse during late gestation. Oxygen transport to tissue II-Advances in experimental medicine and biology Reneau D.D., Grote J.Plenum Press New York 1976 731 736Chapter 75
-
Wilkening R.B., Meschia G.Fetal oxygen uptake, oxygenation and acid-base balance as a function of uterine blood flow. Am. J. Physiol. 244 (Heart Circ. Physiol. 13): H749-H755 1983
-
Wilkening R.B., Meschia G.Comparative physiology of placental oxygen transport Placenta 1992 13 1 15
-
Wilkening R.B., Molina R.D., Meschia G.Placental oxygen transport in sheep with different hemoglobin types. Am. J. Physiol. 254 (Reg. Int. Comp. Physiol. 23): R585–R589 1988
| Insgesamt | Letzte 365 Tage | In den letzten 30 Tagen | |
|---|---|---|---|
| Aufrufe von Kurzbeschreibungen | 132 | 32 | 10 |
| Gesamttextansichten | 6 | 0 | 0 |
| PDF-Downloads | 6 | 0 | 0 |
FETAL OXYGEN SUPPLY AND DEMAND: COMPARATIVE ASPECTS
in Israel Journal of Ecology and EvolutionSearch for other papers by GIACOMO MESCHIA in
Current site
Google Scholar
PubMed
Experimental evidence in six placental mammals (horse, cattle, sheep, man, rhesus monkey, and guinea pig) indicates that fetal O2 uptake per unit fetal body mass does not vary markedly from small to large animals, in sharp contrast to the fact that small adults have a much greater O2 consumption rate per unit body mass than large adults. As a consequence, in an 800-g guinea pig, the mass-specific O2 consumption of the pregnant uterus is less than the mass-specific O2 consumption of the maternal organism, whereas the opposite is true in a 50-kg sheep. This effect of body size on the relationship between maternal and uterine O2 consumption may provide a physiological explanation for the evidence that small mammals are capable of producing a greater total newborn mass in relation to maternal body mass than large mammals.
There are major differences among pregnant mammals in the rate of uterine perfusion which is used to supply O2 to the fetus. Variability in placental structure accounts in part for these differences. In a countercurrent exchange placenta, uterine perfusion can be much smaller than in a venous equilibration exchange placenta and yet provide the same level of fetal oxygenation.
| Insgesamt | Letzte 365 Tage | In den letzten 30 Tagen | |
|---|---|---|---|
| Aufrufe von Kurzbeschreibungen | 132 | 32 | 10 |
| Gesamttextansichten | 6 | 0 | 0 |
| PDF-Downloads | 6 | 0 | 0 |
