EXCRETORY NITROGEN METABOLISM AND GLUCONEOGENESIS DURING DEVELOPMENT OF HIGHER VERTEBRATES
In: Israel Journal of Ecology and EvolutionSearch for other papers by JAMES W. CAMPBELL in
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The concept of nitrogen “excretion” by mammalian and avian embryos is examined in light of contemporary knowledge of hepatic metabolism. The origin of “waste” nitrogen and the hepatic pathways for its conversion to either urea or uric acid for excretion are described. The probable evolution of these pathways among the higher tetrapod vertebrates and the impact of the selective advantage of uricoteley on the radiation of the archosaurs are considered. The intimate connection of hepatic gluconeogenesis with nitrogenous end product formation in birds and mammals is examined. Finally, the development of the capacities for gluconeogenesis and for either ureogenesis or urieogenesis in the perinate is discussed relative to the problem of development in a cleidoic egg.
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EXCRETORY NITROGEN METABOLISM AND GLUCONEOGENESIS DURING DEVELOPMENT OF HIGHER VERTEBRATES
In: Israel Journal of Ecology and EvolutionSearch for other papers by JAMES W. CAMPBELL in
Current site
Google Scholar
PubMed
The concept of nitrogen “excretion” by mammalian and avian embryos is examined in light of contemporary knowledge of hepatic metabolism. The origin of “waste” nitrogen and the hepatic pathways for its conversion to either urea or uric acid for excretion are described. The probable evolution of these pathways among the higher tetrapod vertebrates and the impact of the selective advantage of uricoteley on the radiation of the archosaurs are considered. The intimate connection of hepatic gluconeogenesis with nitrogenous end product formation in birds and mammals is examined. Finally, the development of the capacities for gluconeogenesis and for either ureogenesis or urieogenesis in the perinate is discussed relative to the problem of development in a cleidoic egg.
| All Time | Past 365 days | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 370 | 39 | 4 |
| Full Text Views | 10 | 0 | 0 |
| PDF Views & Downloads | 13 | 0 | 0 |
