THE SPINY MOUSE (ACOMYS CAHIRINUS) â A RODENT PROTOTYPE FOR STUDYING PLASMA VOLUME REGULATION DURING THERMAL DEHYDRATION
In: Israel Journal of Ecology and EvolutionSearch for other papers by MICHAL HOROWITZ in
Current site
Google Scholar
Search for other papers by ARIEH BORUT in
Current site
Google Scholar
During thermal dehydration, extensive mobilization of the evaporative cooling system induces rapid reduction of total body water. The fraction of water contributed to evaporative cooling from each fluid compartment is not equal. Those species which show an ability to conserve their plasma water despite dehydration show better endurance under these stressful conditions. The common spiny mouse (Acomys cahirinus) was a prototype for elucidating the mechanisms underlying plasma volume (PV) conservation. Data accumulated since 1965 on the spiny mouse, as well as on other rodents and larger mammals, suggest that PV conservation during rapid dehydration relies primarily on the ability of the PV conservers to decrease plasma protein extravasation. The mechanisms responsible for this response are coupled to thermally-induced redistribution of cardiac output and to structural changes in the capillary wall. This feature seems to reflect a selective trait for hot, arid environments.
Purchase
Buy instant access (PDF download and unlimited online access):
Institutional Login
Log in with Open Athens, Shibboleth, or your institutional credentials
Personal login
Log in with your brill.com account
-
Adolph E.F., Blood changes in dehydration. Physiology of man in the desert Adolph E.F. et al.Interscience New York 1947 160 171
-
Borut A., Horowitz M., Castel M.Blood volume regulation in the spiny mouse Capillary permeability changes due to dehydration. Comparative physiology of desert animals. Symp. Zool. Soc. London 1972 31 175 189
-
Ellerman J.R., Morrison-Scott T.C.S.Checklist of Palaearctic and Indian mammals 1758â1946 British Museum of Natural History London 1951 810Trustees of the
-
Haddad W., Horowitz M.Heat acclimation alters portal blood flow during heat stress. Pharmacol. Thermoreg., in press 1994
-
Horowitz M.The physiological adaptations of the blood system of desert animals (mice) to dehydration. Ph.D. thesis, Hebrew Univ., Jerusalem (in Hebrew, English summary) 1970
-
Horowitz M., Thermal dehydration and plasma volume regulation: Mechanisms and control. Thermal physiology Hales J.R.S.Raven Press New York 1984 389 394
-
Horowitz M., Adler J.H.Plasma volume regulation during heat stress: Albumin synthesis vs. capillary permeability A comparison between desert and non-desert species. Comp. Biochem. Physiol. A 1983 75 105 110
-
Horowitz M., Borut A.Effect of acute dehydration on body fluid compartments in three rodent species, Rattus norvegicus, Acomys cahirinus Merioness crassus Comp. Biochem. Physiol 1970 35 283 290
-
Horowitz M., Borut A.Blood volume regulation in dehydrated rodents: Plasma proteins turnover and sedimentation coefficients Comp. Biochem. Physiol. A 1975 51 827 831
-
Horowitz M., Borut A.Plasma volume regulation in rodents: Comparison of heat and dehydration effects Isr. J. Med. Sci 1976 12 864 867
-
Horowitz M., Givol N., Heat acclimation and heat stress: Cardiac output distribution, plasma volume expansion and the involvement of the adrenergic pathway Lomax P., Schoenboum E.s. Karger Basel 1989 204 207Thermoregulation: Research and clinical application
-
Horowitz M., Nadel E.R.Effect of plasma volume on thermoregulation in the dog Pflugers Arch 1984 400 211 213
-
Horowitz M., Samueloff S.Plasma water shifts during thermal dehydration J. Appl. Physiol 1979 47 738 744
-
Horowitz M., Samueloff S., Circulation under extreme heat load. Comparative physiology of environmental adaptations Dejour P.s. Karger Basel 1987 94 106Part II. Adaptations to extreme environment
-
Horowitz M., Samueloff S.Cardiac output distribution in thermally dehydrated rodents Am. J. Physiol 1988 254 R109 R116
-
Horowitz M., Samueloff S.Dehydration, stress and heat acclimation Prog. Biometeorol 1989 7 87 95
-
Horowitz M., Samueloff S., Adler J.H.Acute dehydration: Body water distribution in acclimated and non-acclimated P. obesus J. Appl. Physiol 1978 44 585 589
-
Horowitz M., Haddad W., Shochina M., Meiri U., Long term heat acclimation: Acquired peripheral cardiovascular adatpations and their stability under multifactorial stressors. Temperature regulation: Recent physiological and pharmacological advances Milton A.S.Birkhauser Verlag Basel 1994Physiology
-
Kasirer-Israely H., Choshniak I., Shkolnik A.Dehydration and rehydration in donkeys: The role of the hind gut as a water reservoir J. Basic Clin. Physiol. Pharmacol 1994 5 89 100
-
Lee D.H.K., Mulder A.G.Some immediate effects of reduced cooling power upon the water balance and related effects in the human subject J. Physiol. Lond 1935 84 410 432
-
Macfarlane W.V., Robinson K.W., Howard B., Budtz-Olsen O.E.Extracellular fluid distribution in tropical merino sheep Aust. J. Agr. Res 1959 10 269 286
-
Maloiy G.M., Boares C.D.Response of the Somali donkey to dehydration: Hematological changes Am. J. Physiol 1971 221 37 41H
-
Maitz A., Shkolnik A.Milk production in the desert: Lactation and water economy in the black Beduin goat Physiol. Zool 1980 53 12 18
-
Meir M., Shkolnik A.Water economy of slughi, canaan and pointer dogs J. Desert Environ 1984 7 93 99
-
Peled A.Gazella dorcas isabella). M.Sc. thesis, Tel Aviv Univ., Tel Aviv (in Hebrew, English abstr.) 1989Comparative aspects in the physiology of two gazelle species: The mountain gazelle (Gazella gazella) and the desert gazelle
-
Rosenman M., Morrison P.R.The physiological response to heat and dehydration in the guanaco: Lama guanicoe Physiol. Zool 1963 36 45 51
-
Schmidt-Nielsen K.Desert animals Oxford Univ. Press Oxford 1964 33 70
-
Schmidt-Nielson B., Schmidt-Nielson K., Houpt T.R., Jarnum A.S.Water balance of the camel Am. J. Physiol 1956 185 185 194
-
Senay L.C., Christensen M.L.Changes in blood plasma during progressive dehydration J. Appl. Physiol 1964 21 1136 1140
-
Shkolnik A., Borut A.Temperature and water relations in two species of spiny mice (Acomys) J. Mammal 1969 50 245 255
-
Shkolnik A., In: Digestive physiology and metabolism in ruminants. MTP Press, Lancaster, UK Ruckebusch Y., Thidend P.1980
-
Shkolnik A., Choshniak J., Water deprivation and rapid rehydration in the hot and dry terrestrial environment. Comparative physiology: Life in water and on land. Sidia Res. Series Vol Dejours P., Bolis L., Taylor R.C., Werber E.R.Springer Verlag Berlin 1987 9
-
Starling E.H., Production and absorption of lymph. Text book of physiology Schafer E.R.Macmillan New York 1898 296
-
Yousef M.K., Dill D.B., Mayes M.G.Shifts in body fluids during dehydration in the burro, Equus asinus J. Appl. Physiol 1970 23 345 349
-
Zurovsky Y., Shkolnik A., Ovadia M.Conservation of blood plasma fluids in hamadryas baboon after thermal dehydration J. Appl. Physiol 1984 57 763 71
-
Zurovsky Y., Ovadia M., Shkolnik A.Disappearance of dextran 70,000 from plasma of hamadryas baboons Comp. Biochem. Physiol. A 1985 80 373 375
-
Zurovsky Y., Ekstein L., Horowitz M.Heat stress and thermal dehydration: Lactacidemia and plasma volume regulation J. Appl. Physiol 1991 71 2434 2439
| All Time | Past 365 days | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 99 | 12 | 0 |
| Full Text Views | 11 | 0 | 0 |
| PDF Views & Downloads | 10 | 0 | 0 |
THE SPINY MOUSE (ACOMYS CAHIRINUS) â A RODENT PROTOTYPE FOR STUDYING PLASMA VOLUME REGULATION DURING THERMAL DEHYDRATION
In: Israel Journal of Ecology and EvolutionSearch for other papers by MICHAL HOROWITZ in
Current site
Google Scholar
PubMed
Search for other papers by ARIEH BORUT in
Current site
Google Scholar
PubMed
During thermal dehydration, extensive mobilization of the evaporative cooling system induces rapid reduction of total body water. The fraction of water contributed to evaporative cooling from each fluid compartment is not equal. Those species which show an ability to conserve their plasma water despite dehydration show better endurance under these stressful conditions. The common spiny mouse (Acomys cahirinus) was a prototype for elucidating the mechanisms underlying plasma volume (PV) conservation. Data accumulated since 1965 on the spiny mouse, as well as on other rodents and larger mammals, suggest that PV conservation during rapid dehydration relies primarily on the ability of the PV conservers to decrease plasma protein extravasation. The mechanisms responsible for this response are coupled to thermally-induced redistribution of cardiac output and to structural changes in the capillary wall. This feature seems to reflect a selective trait for hot, arid environments.
| All Time | Past 365 days | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 99 | 12 | 0 |
| Full Text Views | 11 | 0 | 0 |
| PDF Views & Downloads | 10 | 0 | 0 |
