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In vitro binding of mutagenic heterocyclic aromatic amines by Bifidobacterium pseudocatenulatum G4
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Abstract
Consumption of probiotics has been associated with decreased risk of colon cancer and reported to have anti-mutagenic/anti-carcinogenic properties. One possible mechanism for this effect involves physical binding of the mutagenic compounds, such as heterocyclic amines (HCAs), to the bacteria. Therefore, the objective of this study was to examine the binding capacity of bifidobacterial strains of human origin on mutagenic heterocyclic amines which are suspected to play a role in human cancers. In vitro binding of the mutagens Trp-p-2, IQ, MeIQx, 7,8DiMeIQx and PhIP by three bacterial strains in two media of different pH was analysed using high performance liquid chromatography. Bifidobacterium pseudocatenulatum G4 showed the highest decrease in the total HCAs content, followed by Bifidobacterium longum, and Escherichia coli. pH affects binding capacity; the highest binding was obtained at pH 6.8. Gram-positive tested strains were found to be consistently more effective than the gram-negative strain. There were significant decreases in the amount of HCAs in the presence of different cell concentrations of B. pseudocatenulatum G4; the highest decrease was detected at the concentration of 1010 cfu/ml. The results showed that HCAs were able to bind with all bacterial strains tested in vitro, thus it may be possible to decrease their absorption by human intestine and increase their elimination via faeces.
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Ali, Q.S., Farid, A.J., Kabeir, B.M., Zamberi, S., Shuhaimi, M., Ghazali, H. and Yazid, A.M., 2009. Adhesion properties of Bifidobacterium pseudocatenulatum G4 and Bifidobacterium longum BB536 on HT-29 human epithelium cell line at different times and pH. Proceedings World Academy of Science, Engineering and Technology 37: 2070-3740.
'Adhesion properties of Bifidobacterium pseudocatenulatum G4 and Bifidobacterium longum BB536 on HT-29 human epithelium cell line at different times and pH ' () 37 Proceedings World Academy of Science, Engineering and Technology : 2070 -3740.
-
Armindo, M., Olga, V. and Catarina, P., 2008. Effect of beer/red wine marinades on the formation of heterocyclic aromatic amines in pan-fried beef. Agricultural and Food Chemistry 56: 10625-10632.
'Effect of beer/red wine marinades on the formation of heterocyclic aromatic amines in pan-fried beef ' () 56 Agricultural and Food Chemistry : 10625 -10632.
-
Bolognani, F., Rumney, C.J. and Rowland, I.R., 1997. Influence of carcinogen binding by lactic acid-producing bacteria on tissue distribution and in vivo mutagenicity of dietary carcinogens. Food and Chemical Toxicology 35: 535-545.
'Influence of carcinogen binding by lactic acid-producing bacteria on tissue distribution and in vivo mutagenicity of dietary carcinogens ' () 35 Food and Chemical Toxicology : 535 -545.
-
Capurso, G., Marignani, M. and Delle Fave, G., 2006. Probiotics and the incidence of colorectal cancer: when evidence is not evident. Digestive and Liver Disease 38: 277-282.
'Probiotics and the incidence of colorectal cancer: when evidence is not evident ' () 38 Digestive and Liver Disease : 277 -282.
-
Cheng, K-W., Chen, F. and Wang, M., 2006. Heterocyclic amines: chemistry and health. Molecular Nutrition and Food Research 50: 1150-1170.
-
Collado, M.C., Meriluoto, J. and Salminen, S., 2007. In vitro analysis of probiotic strain combinations to inhibit pathogen adhesion to human intestinal mucus. Journal of Food Research International 40: 629-636.
-
Delgado, S., Flórez, A.B. and Mayo, B., 2005. Antibiotic susceptibility of Lactobacillus and Bifidobacterium species from the human gastrointestinal tract. Current Microbiology 50: 202-207.
'Antibiotic susceptibility of Lactobacillus and Bifidobacterium species from the human gastrointestinal tract ' () 50 Current Microbiology : 202 -207.
-
Gooderham, N.J., Creton, S., Lauber, S.N. and Zhu, H., 2007. Mechanisms of action of the carcinogenic heterocyclic amine PhIP. Journal of Toxicology Letters 168: 269-277.
'Mechanisms of action of the carcinogenic heterocyclic amine PhIP ' () 168 Journal of Toxicology Letters : 269 -277.
-
Hughes, D.B. and Hoover, D.G., 1991. Bifidobacteria: their potential for use in American dairy products. Journal of Food Technology 45: 74-79.
'Bifidobacteria: their potential for use in American dairy products ' () 45 Journal of Food Technology : 74 -79.
-
International Agency for Research on Cancer (IARC), 1977. Dietary fibre, transit time, faecal bacteria, steroids, and colon cancer in two Scandinavian populations. The Lancet 2: 207-211.
-
Kabeir, B.M., Yazid, A.M., Stephenie, W., Nazrul Hakim, M., Muhammad Anas, O. and Shuhaimi, M., 2008. Safety evaluation of Bifidobacterium pseudocatenulatum G4 as assessed in BALB/c mice. Letters in Applied Microbiology 46: 32-37.
'Safety evaluation of Bifidobacterium pseudocatenulatum G4 as assessed in BALB/c mice ' () 46 Letters in Applied Microbiology : 32 -37.
-
Lankaputhra, W.E.V. and Shah, N.P., 1998. Antimutagenic properties of probiotic bacteria and of organic acids. Journal of Mutation Research 397: 169-182.
-
Lo, P.R., Yu, R.C., Chou, C.C. and Huang, E.C., 2004. Determinations of the antimutagenic activities of several probiotic bifidobacteria under acidic and bile conditions against benzo[a]pyrene by a modified Ames test. International Journal of Food Microbiology 93: 249-257.
-
Malhotra, S.L., 1977. Dietary factors in a study of colon cancer from cancer registry, with special reference to the role of saliva, milk, and fermented milk products and vegetable fiber. Journal of Medical Hypotheses 3: 122-134.
'Dietary factors in a study of colon cancer from cancer registry, with special reference to the role of saliva, milk, and fermented milk products and vegetable fiber ' () 3 Journal of Medical Hypotheses : 122 -134.
-
Mariam, R.S., Yap, K.W., Lim, L.C., Kharidah, M., Shuhaimi, M., Abdullah, S., Ali, AM., Atiqah, A.N. and Yazid, A.M., 2004. Strain differences in deconjugation of bile acids in Bifidobacterium pseudocatenulatum isolates. Journal of Bioscience Microflora 23: 93-98.
'Strain differences in deconjugation of bile acids in Bifidobacterium pseudocatenulatum isolates ' () 23 Journal of Bioscience Microflora : 93 -98.
-
Melo, A., Viegas, O., Petisca, C., Pinho, O. and Ferreira, I.M.P.L.V.O., 2008. Effect of beer/red wine marinades on the formation of heterocyclic aromatic amines in pan-fried beef. Agricultural and Food Chemistry 56: 10625-10632.
'Effect of beer/red wine marinades on the formation of heterocyclic aromatic amines in pan-fried beef ' () 56 Agricultural and Food Chemistry : 10625 -10632.
-
Morotomi, M. and Mutai, M., 1986. In vitro binding of potent mutagenic pyrolysates to intestinal bacteria. Journal of National Cancer Institute 77: 195-201.
'In vitro binding of potent mutagenic pyrolysates to intestinal bacteria ' () 77 Journal of National Cancer Institute : 195 -201.
-
Nowak, A., Arabski, M. and Libudzisz, Z., 2008. Ability of intestinal lactic acid bacteria to bind and/or metabolise indole. Food Technology and Biotechnology Journal 46: 299-304.
'Ability of intestinal lactic acid bacteria to bind and/or metabolise indole ' () 46 Food Technology and Biotechnology Journal : 299 -304.
-
O'Mahony, L., Feeney, M. and O'Halloran, S., 2001. Probiotic impact on microbial flora, inflammation and tumor development in IL-10 knockout mice. Journal of Alimentary Pharmacology and Therapeutics 15: 1219-1225.
'Probiotic impact on microbial flora, inflammation and tumor development in IL-10 knockout mice ' () 15 Journal of Alimentary Pharmacology and Therapeutics : 1219 -1225.
-
Onoue, M., Kado, S., Sakaitani, Y., Uchida, K. and Morotomi, M., 1997. Specific species of intestinal bacteria influence the induction of aberrant crypt foci by 1,2-dimethyl hydrazine in rats. Cancer Letters 113: 179-186.
'Specific species of intestinal bacteria influence the induction of aberrant crypt foci by 1,2-dimethyl hydrazine in rats ' () 113 Cancer Letters : 179 -186.
-
Orrhage, K., Sillerström, E., Gustafsson, J.-A., Nord, C.E. and Rafter, J., 1994. Binding of mutagenic heterocyclic amines by intestinal and lactic acid bacteria. Journal of Mutation Research 311: 239-248.
-
Rafter, J., 2003. Probiotics and cancer. Journal of Best Practice and Research, Clinical Gastroenterology 17: 849-859.
'Probiotics and cancer ' () 17 Journal of Best Practice and Research, Clinical Gastroenterology : 849 -859.
-
Reddy, B. and Rivenson, A., 1993. Inhibitory effect of Bifidobacterium longum on colon, mammary, and liver carcinogenesis induced by 2-amino-3-methylimidazo [4,5-f] quinoline, a food mutagen. Journal of Cancer Research 53: 3914-3918.
-
Salminen, S., Bouley, C. and Boutron-Ruault, M.C., 1998. Functional food science and gastrointestinal physiology and function. British Journal of Nutrition 80: 147-171.
'Functional food science and gastrointestinal physiology and function ' () 80 British Journal of Nutrition : 147 -171.
-
Shuhaimi, M., Ali, A.M., Norjihan, M.S. and Yazid, A.M., 2002. Classification of Bifidobacterium isolates from infant faeces using PCR-based and16S rDNA Partial Sequences Analysis methods. Bioscience Microflora 21: 155-161.
'Classification of Bifidobacterium isolates from infant faeces using PCR-based and16S rDNA Partial Sequences Analysis methods ' () 21 Bioscience Microflora : 155 -161.
-
Shuhaimi, M., Ali, A.M., Norjihan, M.S., Khatijah, Y. and Yazid, A.M., 2001. Differentiation of the Bifidobacterium pseudocatenulatum isolates from faeces of infant by RAPD. Bioscience Microflora 20: 89-94.
'Differentiation of the Bifidobacterium pseudocatenulatum isolates from faeces of infant by RAPD ' () 20 Bioscience Microflora : 89 -94.
-
Shuhaimi, M., Yazid, A.M., Ali, A.M., Ghazali, M.H., Zaitun, H. and Atiqah, N.A., 1999. Acid adaptation of bifidobacteria isolated from infant stools to simulated pH of human stomach. Pakistan Journal of Biological Sciences 2: 1203-1206.
'Acid adaptation of bifidobacteria isolated from infant stools to simulated pH of human stomach ' () 2 Pakistan Journal of Biological Sciences : 1203 -1206.
-
Smith, J.S., Ameri, F. and Gadgil, P., 2008. Effect of marinades on the formation of heterocyclic amines in grilled beef steaks. Journal of Food Science 73: T100-T105.
'Effect of marinades on the formation of heterocyclic amines in grilled beef steaks ' () 73 Journal of Food Science : T100 -T105.
-
Stephenie, W., Kabeir, B.M., Shuhaimi, M., Rosfarizan, M. and Yazid, A.M., 2007. Growth optimization of a probiotic candidate, Bifidobacterium pseudocatenulatum G4, in milk medium using response surface methodology. Journal of Biotechnology and Bioprocess Engineering 12: 106-113.
'Growth optimization of a probiotic candidate, Bifidobacterium pseudocatenulatum G4, in milk medium using response surface methodology ' () 12 Journal of Biotechnology and Bioprocess Engineering : 106 -113.
-
Sugimura, T., Nagao, N., Kawachi, T., Honda, M., Yahagi, T., Seino, Y., Stao, S., Matsukura, N., Matsushima, T., Shirai, A., Sawamura, M. and Matsumoto, H., 1977. Mutagen-carcinogens in food, with special reference to highly mutagenic pyrolytic products in boiled foods. In: Hiatt, H.H., Watson, J.D. and Winstein, J.A. (eds.) Origins of human cancer. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA, pp. 1561-1577.
-
Sugimura, T., Wakabayashi, K., Nakagama, H. and Nagao, M., 2004. Heterocyclic amines: mutagens/carcinogens produced during cooking of meat and fish. Journal of Cancer Science 95: 290-299.
'Heterocyclic amines: mutagens/carcinogens produced during cooking of meat and fish ' () 95 Journal of Cancer Science : 290 -299.
-
Terahara, M., Meguro, S. and Kaneko, T., 1998. Effects of lactic acid bacteria on binding and absorption of mutagenic heterocyclic amines. Journal of Bioscience, Biotechnology and Biochemistry 62: 197-200.
'Effects of lactic acid bacteria on binding and absorption of mutagenic heterocyclic amines ' () 62 Journal of Bioscience, Biotechnology and Biochemistry : 197 -200.
-
Trejo, F.M., Minnaard, J., Perez, P.F. and De Antoni, G.L., 2006. Inhibition of Clostridium difficile growth and adhesion to enterocytes by Bifidobacterium supernatants. Anaerobe 12: 186-193.
-
Wilson, M., 2005. Microbial inhabitants of human: their ecology and role in health and disease. Cambridge University Press, Camebridge, UK. 476 pp.
-
Wollowski, I., Rechkemmer, G. and Pool-Zobel, B.L., 2001. Protective role of probiotics and prebiotics in colon cancer. American Journal of Clinical Nutrition 73: 451-455.
'Protective role of probiotics and prebiotics in colon cancer ' () 73 American Journal of Clinical Nutrition : 451 -455.
-
Wong, S., Wendy, Y.K., Kabeir, B.M., Shuhaimi, M., Rosfarizan, M. and Yazid, A.M., 2006. Survival of Bifidobacterium pseudocatenulatum strains isolated from beast-fed infants to simulated gastric pH environment. Malaysian Applied Biology 35: 57-62.
'Survival of Bifidobacterium pseudocatenulatum strains isolated from beast-fed infants to simulated gastric pH environment ' () 35 Malaysian Applied Biology : 57 -62.
-
Yazid, A.M., Ali, A.M., Shuhaimi, M., Kalaivaani, V., Rokiah, M.Y. and Reezal, A., 2000. Antimicrobial susceptibility of bifidobacteria. Letters in Applied Microbiology 31: 57-62.
'Antimicrobial susceptibility of bifidobacteria ' () 31 Letters in Applied Microbiology : 57 -62.
-
Yun, S.-I., 2004. The binding of Bacillus natto isolated from natto to heterocyclic pyrolysates. World Journal of Microbiology and Biotechnology 20: 469-474.
'The binding of Bacillus natto isolated from natto to heterocyclic pyrolysates ' () 20 World Journal of Microbiology and Biotechnology : 469 -474.
-
Zhang, X.B. and Ohta, Y., 1991. Binding of mutagens by fractions of the cell wall skeleton by lactic acid bacteria on mutagens. Journal of Dietary Science 74: 1477-1481.
'Binding of mutagens by fractions of the cell wall skeleton by lactic acid bacteria on mutagens ' () 74 Journal of Dietary Science : 1477 -1481.
-
Zhang, X.B., Ohta, Y. and A. Hosono, 1990. Antimutagenicity and binding of lactic acid bacteria from a Chinese cheese to mutagenic pyrolyzates. Journal of Dairy Science 73: 2702-2710.
'Antimutagenicity and binding of lactic acid bacteria from a Chinese cheese to mutagenic pyrolyzates ' () 73 Journal of Dairy Science : 2702 -2710.
| Insgesamt | Letzte 365 Tage | In den letzten 30 Tagen | |
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| Aufrufe von Kurzbeschreibungen | 353 | 145 | 9 |
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In vitro binding of mutagenic heterocyclic aromatic amines by Bifidobacterium pseudocatenulatum G4
in Beneficial MicrobesSearch for other papers by F. Faridnia in
Current site
Google Scholar
PubMed
Search for other papers by A.S.M. Hussin in
Current site
Google Scholar
PubMed
Search for other papers by N. Saari in
Current site
Google Scholar
PubMed
Search for other papers by S. Mustafa in
Current site
Google Scholar
PubMed
Search for other papers by L.Y. Yee in
Current site
Google Scholar
PubMed
myazid@putra.upm.edu.my
Search for other papers by M.Y.A. Manap in
Current site
Google Scholar
PubMed
Abstract
Consumption of probiotics has been associated with decreased risk of colon cancer and reported to have anti-mutagenic/anti-carcinogenic properties. One possible mechanism for this effect involves physical binding of the mutagenic compounds, such as heterocyclic amines (HCAs), to the bacteria. Therefore, the objective of this study was to examine the binding capacity of bifidobacterial strains of human origin on mutagenic heterocyclic amines which are suspected to play a role in human cancers. In vitro binding of the mutagens Trp-p-2, IQ, MeIQx, 7,8DiMeIQx and PhIP by three bacterial strains in two media of different pH was analysed using high performance liquid chromatography. Bifidobacterium pseudocatenulatum G4 showed the highest decrease in the total HCAs content, followed by Bifidobacterium longum, and Escherichia coli. pH affects binding capacity; the highest binding was obtained at pH 6.8. Gram-positive tested strains were found to be consistently more effective than the gram-negative strain. There were significant decreases in the amount of HCAs in the presence of different cell concentrations of B. pseudocatenulatum G4; the highest decrease was detected at the concentration of 1010 cfu/ml. The results showed that HCAs were able to bind with all bacterial strains tested in vitro, thus it may be possible to decrease their absorption by human intestine and increase their elimination via faeces.
| Insgesamt | Letzte 365 Tage | In den letzten 30 Tagen | |
|---|---|---|---|
| Aufrufe von Kurzbeschreibungen | 353 | 145 | 9 |
| Gesamttextansichten | 6 | 3 | 1 |
| PDF-Downloads | 11 | 3 | 0 |
