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Ergogenic effects of phosphatidylserine alone and combined with branched-chain amino acids in trained rats
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Acute phosphatidylserine (PS) or branched-chain amino acids (BCAA) supplements alone may have an adrenocorticotropic hormone, cortisol suppressive effect and increase the testosterone/cortisol ratio, but the associated effect of these supplements during a period of high-intensity physical stress is not yet known. The study investigated the effects of chronic PS supplementation alone and combined with BCAA during high-intensity interval training (HIIT) on training volume tolerance, anabolic-catabolic balance and stress biomarkers in rats. Thirty-three rats were separated into: placebo (PLA, n=11), PS alone (n=11) and combined with BCAA (PSBCAA, n=11). Groups performed swimming sessions of HIIT (5 series × 1 min × 1 min recovery; external load equivalent to 13% of body mass) and nine recovery sessions of moderate-intensity training (30 min at 5% of body mass) alternately. One-way ANOVA was used to compare biochemical variables and two-way ANOVA was calculated to compare training volume. Training volume performed (TVP) was higher in first, fourth, fifth, sixth, and eighth HIIT sessions in the PS group in comparison to PLA (P<0.05). TVP was higher in the fourth session in PSBCAA compared to PLA. There were no differences in TVP during the sessions between PS and BCAA groups. Creatine kinase (CK) was lower in PSBCAA in comparison to PS alone (P=0.03) and PLA (P=0.04) after the experimental period. Testosterone concentration was enhanced in PSBCAA group compared to PLA (P=0.01); testosterone/corticosterone ratio was higher in PSBCAA compared to PS (P=0.05) and PLA (P=0.004) after protocol. PS combined with BCAA increases testosterone concentration and testosterone/corticosterone ratio, demonstrating an enhancement of anabolic state in trained rats.
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Carli, G., Bonifazi, M., Lodi, L., Lupo, C., Martelli, G. and Viti, A., 1992. Changes in the exercise-induced hormone response to branched chain amino acid administration. European Journal of Applied Physiology and Occupational Physiology 64: 272-277. https://doi.org/10.1007/BF00626291
-
Casella, S., Vazzana, I., Giudice, E., Fazio, F. and Piccione, G., 2016. Relationship between serum cortisol levels and some physiological parameters following reining training session in horse. Animal Science Journal 87: 729-735.
'Relationship between serum cortisol levels and some physiological parameters following reining training session in horse ' () 87 Animal Science Journal : 729 -735.
-
Cenacchi, T., Bertoldin, T., Farina, C., Fiori, M.G., Crepaldi, G. and Azzini, C.F., 1993. Cognitive decline in the elderly: A doubleblind, placebo-controlled multicenter study on efficacy of phosphatidylserine administration. Aging Clinical and Experimental Research 5: 123-133. 10.1007/bf03324139
'Cognitive decline in the elderly: A doubleblind, placebo-controlled multicenter study on efficacy of phosphatidylserine administration ' () 5 Aging Clinical and Experimental Research : 123 -133.
-
Contarteze, R.V., Manchado F, B., Gobatto, C.A. and De Mello, M.A., 2008. Stress biomarkers in rats submitted to swimming and treadmill running exercises. Comparative Biochemistry and Physiology Part A 151: 415-422. https://doi.org/10.1016/j.cbpa.2007.03.005
-
Coombes, J.S. and McNaughton, L.R., 2000. Effects of branched-chain amino acid supplementation on serum creatine kinase and lactate dehydrogenase after prolonged exercise. Journal of Sports Medicine and Physical Fitness 40: 240-246.
'Effects of branched-chain amino acid supplementation on serum creatine kinase and lactate dehydrogenase after prolonged exercise ' () 40 Journal of Sports Medicine and Physical Fitness : 240 -246.
-
Cottin, F., Barrey, E., Lopes, P. and Billat, V., 2006. Effect of repeated exercise and recovery on heart rate variability in elite trotting horses during high intensity interval training. Equine Veterinary Journal Suppl. 36: 204-209.
'Effect of repeated exercise and recovery on heart rate variability in elite trotting horses during high intensity interval training ' () 36 Equine Veterinary Journal : 204 -209.
-
De Araujo, G.G., Papoti, M., Dos Reis, I.G., De Mello, M.A. and Gobatto, C.A., 2016. Short and long term effects of high-intensity interval training on hormones, metabolites, antioxidant system, glycogen concentration, and aerobic performance adaptations in rats. Frontiers in Physiology 7: 505. https://doi.org/10.3389/fphys.2016.00505
-
De Araujo, G.G., Papoti, M., Dos Reis, I.G.M., De Mello, M.A. and Gobatto, C.A., 2012 Physiological responses during linear periodized training in rats. European Journal of Applied Physiology 112: 839-852.
'Physiological responses during linear periodized training in rats ' () 112 European Journal of Applied Physiology : 839 -852.
-
De Araujo, G.G., Papoti, M., Manchado F.B., de Mello, M.A. and Gobatto, C.A., 2007. Protocols for hyperlactatemia induction in the lactate minimum test adapted to swimming rats. Comparative Biochemistry and Physiology Part A 148: 888-892.
'Protocols for hyperlactatemia induction in the lactate minimum test adapted to swimming rats ' () 148 Comparative Biochemistry and Physiology Part A : 888 -892.
-
Doma, K., Singh, U., Boullosa, D. and Connor, J.D., 2021. The effect of branched-chain amino acid on muscle damage markers and performance following strenuous exercise: a systematic review and meta-analysis. Applied Physiology, Nutrition, and Metabolism 46: 1303-1313. https://doi.org/10.1139/apnm-2021-011
-
Dubois, M., Gilles, K.A., Hamilton, J.K., Rebers, P.A. and Smith, F., 1956. Colorimetric method for determination of sugars and related substances. Analytical Chemistry 28: 350-356.
'Colorimetric method for determination of sugars and related substances ' () 28 Analytical Chemistry : 350 -356.
-
Fahey, T. and Pearl, M., 1998. The hormonal and perceptive effects of phosphatidylserine administration during two weeks of resistive exercise-induced overtraining. Biology of Sport 15: 135-144.
'The hormonal and perceptive effects of phosphatidylserine administration during two weeks of resistive exercise-induced overtraining ' () 15 Biology of Sport : 135 -144.
-
Fernholz, K.M., Seifert, J.G., Bacharach, D.W., Burke, E.R. and Gazal, O., 2000. The effects of phosphatidyl serine on markers of muscular stress in endurance runners. Dissertation, St. Cloud State University, St Cloud, MN, USA.
'The effects of phosphatidyl serine on markers of muscular stress in endurance runners', ().
-
Fournier, P.A., Fairchild, T.J., Ferreira, L.D. and Brau, L., 2004. Postexercise muscle glycogen repletion in the extreme: effect of food absence and active recovery. Journal of Sports Science and Medicine 3: 139-146.
'Postexercise muscle glycogen repletion in the extreme: effect of food absence and active recovery ' () 3 Journal of Sports Science and Medicine : 139 -146.
-
Gondim, F.J., Zoppi, C.C., Pereira-da-Silva, L. and De Macedo, D.V., 2006. Determination of the anaerobic threshold and maximal lactate steady state speed in equines using the lactate minimum speed protocol. Comparative Biochemistry and Physiology Part A 146: 375-380.
'Determination of the anaerobic threshold and maximal lactate steady state speed in equines using the lactate minimum speed protocol ' () 146 Comparative Biochemistry and Physiology Part A : 375 -380.
-
Gore, D.C., Jahoor, F., Wolfe, R.R. and Herndon, D.N., 1993. Acute response of human muscle protein to catabolic hormones. Annals of Surgery 218: 679-684.
'Acute response of human muscle protein to catabolic hormones ' () 218 Annals of Surgery : 679 -684.
-
Gualano, A.B., Bozza, T., Campos-Ferraz, P.L., Roschel, H., Dos Santos, C.A., Marquezi, M.L., Benatti, F. and Lancha Junior, H.A., 2011. Branched chain amino acids supplementation enhance exercise capacity and lipid oxidation during endurance exercise after muscle glycogen depletion. The Journal of Sports Medicine and Physical Fitness 51: 82-88.
'Branched chain amino acids supplementation enhance exercise capacity and lipid oxidation during endurance exercise after muscle glycogen depletion ' () 51 The Journal of Sports Medicine and Physical Fitness : 82 -88.
-
Harriss, D.J., MacSween, A. and Atkinson, G., 2019. Ethical standards in sport and exercise science research: 2020 update. International Journal of Sports Medicine 40: 813-817. https://doi.org/10.1055/a-1015-3123
-
Hohl, R., Ferraresso, R.L., De Oliveira, R.B., Lucco, R., Brenzikofer, R. and De Macedo, D.V., 2009. Development and characterization of an overtraining animal model. Medicine and Science in Sports and Exercise 41: 1155-1163. https://doi.org/10.1249/MSS.0b013e318191259c
-
Jager, R., Purpura, M. and Kingsley, M., 2007. Phospholipids and sports performance. Journal of the International Society of Sports Nutrition 4: 5. https://doi.org/10.1186/1550-2783-4-5
-
Jamurtas, A.Z., Fatouros, I.G, Deli, C.K, Georgakouli, K., Poulios, A., Draganidis, D., Papanikolaou, K., Tsimeas, P., Chatzinikolaou, A., Avloniti, A., Tsiokanos, A. and Koutedakis, Y., 2018. The effects of acute low-volume HIIT and aerobic exercise on leukocyte count and redox status. Journal of Sports Science and Medicine 17: 501-508.
'The effects of acute low-volume HIIT and aerobic exercise on leukocyte count and redox status ' () 17 Journal of Sports Science and Medicine : 501 -508.
-
Jensen, J., Rustad, P.I., Kolnes, A.J. and Lai, Y.C., 2011. The role of skeletal muscle glycogen breakdown for regulation of insulin sensitivity by exercise. Frontiers in Physiology 2: 112. https://doi.org/10.3389/fphys.2011.00112
-
Ji, L.L., 1993. Antioxidant enzyme response to exercise and aging. Medicine and Science in Sports and Exercise 25: 225-231
'Antioxidant enzyme response to exercise and aging ' () 25 Medicine and Science in Sports and Exercise : 225 -231.
-
Kędzierski, W., Cywińska., A, Strzelec., K. and Kowalik., S., 2014. Changes in salivary and plasma cortisol levels in Purebred Arabian horses during race training session. Animal Science Journal 85: 313-317.
'Changes in salivary and plasma cortisol levels in Purebred Arabian horses during race training session ' () 85 Animal Science Journal : 313 -317.
-
Kim, D.H., Kim, S.H., Jeong, W.S. and Lee, H.Y., 2013. Effect of BCAA intake during endurance exercises on fatigue substances, muscle damage substances, and energy metabolism substances. Journal of Exercise Nutrition and Biochemistry 17: 169-180. https://doi.org/10.5717/jenb.2013.17.4.169
-
Kingsley, M.I., Kilduff, L.P., McEneny, J., Dietzig, R.E. and Benton, D., 2006a. Phosphatidylserine supplementation and recovery following downhill running. Medicine and Science in Sports and Exercise 38: 1617-1625. https://doi.org/10.1249/01.mss.0000229459.11452.a0
-
Kingsley, M.I., Miller, M., Kilduff, L.P., McEneny, J. and Benton, D., 2006b. Effects of phosphatidylserine on exercise capacity during cycling in active males. Medicine and Science in Sports and Exercise 38: 64-71. https://doi.org/10.1249/01.mss.0000183195.10867.d0
-
Kingsley, M.I., Wadsworth, D., Kilduff, L.P., McEneny, J. and Benton, D., 2005. Effects of phosphatidylserine on oxidative stress following intermittent running. Medicine and Science in Sports and Exercise 37: 1300-1306. https://doi.org/10.1249/01.mss.0000175306.05465.7e
-
Kirwan, J.P., Clarkson, P.M., Graves, J.E., Litchfield, P.L., and Byrnes, W.C., 1986. Levels of serum creatine kinase and myoglobin in women after two isometric exercise conditions. European Journal of Applied Physiology 55: 330-333.
'Levels of serum creatine kinase and myoglobin in women after two isometric exercise conditions ' () 55 European Journal of Applied Physiology : 330 -333.
-
Laursen, P.B. and Jenkins, D.G., 2002. The scientific basis for high-intensity interval training: optimising training programmes and maximising performance in highly trained endurance athletes. Sports Medicine 32: 53-73. https://doi.org/10.2165/00007256-200232010-00003
-
Liu, S.H., Chang, C.D., Chen, P.H., Su, J.R., Chen, C.C. and Chaung, H.C., 2012. Docosahexaenoic acid and phosphatidylserine supplementations improve antioxidant activities and cognitive functions of the developing brain on pentylenetetrazol-induced seizure model. Brain Research 1451: 19-26. https://doi.org/10.1016/j.brainres.2012.02.060
-
MacInnis, M.J. and Gibala, M.J., 2017. Physiological adaptations to interval training and the role of exercise intensity. Journal of Physiology 595: 2915-2930. https://doi.org/10.1113/JP273196
-
Maillard, F., Pereira, B. and Boisseau, N., 2018. Effect of high-intensity interval training on total, abdominal and visceral fat mass: a metaanalysis. Sports Medicine 48: 269-288. https://doi.org/10.1007/s40279-017-0807-y
-
Manchado, F.B., Gobatto, C.A., Voltarelli, F.A. and Rostom de Mello, M.A., 2006. Non-exhaustive test for aerobic capacity determination in swimming rats. Applied Physiology, Nutrition, and Metabolism 31: 731-736. https://doi.org/10.1139/h06-079
-
Mantuano, P., Bianchini, G., Cappellari, O., Boccanegra, B., Conte, E., Sanarica, F., Mele, A, Camerino, G.M., Brandolini, L., Allegretti, M., De Bellis, M., Aramini, A. and De Luca, A., 2020. Ergogenic effect of BCAAs and L-alanine supplementation: proof-of-concept study in a murine model of physiological exercise. Nutrients 12: 2295.
'Ergogenic effect of BCAAs and L-alanine supplementation: proof-of-concept study in a murine model of physiological exercise ' () 12 Nutrients : 2295.
-
McArdle, W. and Montoye, H., 1966. Reability of exhaustive swimming in the laboratory rat. Journal of Applied Physiology 21: 1431-1434.
'Reability of exhaustive swimming in the laboratory rat ' () 21 Journal of Applied Physiology : 1431 -1434.
-
Mellman, W.J., Schimke, R.T. and Hayflick, L. 1972. Catalase turnover in human diploid cell cultures. Experimental Cell Research 73: 399-409. https://doi.org/10.1016/0014-4827(72)90064-x
-
Monteleone, P., Beinat, L., Tanzillo, C., Maj, M. and Kemali, D., 1990. Effects of phosphatidylserine on the neuroendocrine response to physical stress in humans. Neuroendocrinology 52: 243-248. https://doi.org/10.1159/000125593
-
Monteleone, P., Maj, M., Beinat, L., Natale, M. and Kemali, D., 1992. Blunting by chronic phosphatidylserine administration of the stress-induced activation of the hypothalamo-pituitary-adrenal axis in healthy men. European Journal of Clinical Pharmacology 42: 385-388. https://doi.org/10.1007/BF00280123
-
Morrot, G., Zachowski, A. and Devaux, P.F., 1990. Partial purification and characterization of the human erythrocyte Mg2(+)-ATPase. A candidate aminophospholipid translocase. FEBS Letters 266: 29-32. https://doi.org/10.1016/0014-5793(90)81498-d
-
Negro, M., Giardina, S., Marzani, B. and Marzatico, F., 2008. Branched-chain amino acid supplementation does not enhance athletic performance but affects muscle recovery and the immune system. Journal of Sports Medicine and Physical Fitness 48: 347-351.
'Branched-chain amino acid supplementation does not enhance athletic performance but affects muscle recovery and the immune system ' () 48 Journal of Sports Medicine and Physical Fitness : 347 -351.
-
Olfert, E., Cross, B., McWilliam, D. and McWilliam, A., 1997. Guidelines for the use of animals in psychology. Canadian Council on Animal Care (CCAC), Ottawa, ON, Canada.
'Guidelines for the use of animals in psychology', ().
-
Pillis, W., Zarzeczny, R., Langfort, J., Kaciuba-Uscilko, H., Nazar, K., Wojtyna, J., 1993. Anaerobic threshold in rats. Comparative Biochemistry and Physiology Part A 106: 285-289.
'Anaerobic threshold in rats ' () 106 Comparative Biochemistry and Physiology Part A : 285 -289.
-
Rasmussen, B.B., Tipton, K.D., Miller, S.L., Wolf, S.E. and Wolfe, R.R., 2000. An oral essential amino acid-carbohydrate supplement enhances muscle protein anabolism after resistance exercise. Journal of Applied Physiology 88: 386-392. https://doi.org/10.1152/jappl.2000.88.2.386
-
Sharp, C.P.M. and Pearson, D.R., 2010. Amino acid supplements and recovery from high-intensity resistance training. Journal of Strength and Conditioning Research 24: 1125-1130. https://doi.org/10.1519/JSC.0b013e3181c7c655
-
Shimomura, Y., Inaguma, A., Watanabe, S., Yamamoto, Y., Muramatsu, Y., Bajotto, G., Sato, J., Shimomura, N., Kobayashi, H. and Mawatari, K., 2010. Branched-chain amino acid supplementation before squat exercise and delayed-onset muscle soreness. International Journal of Sport Nutrition and Exercise Metabolism 20: 236-244. https://doi.org/10.1123/ijsnem.20.3.236
-
Specht, S.C. and Robinson, J.D., 1973. Stimulation of the (Na+ + K+)-dependent adenosine triphosphatase by amino acids and phosphatidylserine: chelation of trace metal inhibitors. Archives of Biochemistry and Biophysics 154: 314-323. https://doi.org/10.1016/0003-9861(73)90063-5
-
Starks, M.A., Starks, S.L., Kingsley, M., Purpura, M. and Jager, R., 2008. The effects of phosphatidylserine on endocrine response to moderate intensity exercise. Journal of the International Society of Sports Nutrition 5: 11. https://doi.org/10.1186/1550-2783-5-11
-
Totsuka, M., Nakaji, S., Suzuki, K., Sugawara, K. and Sato, K., 2002. Break point of serum creatine kinase release after endurance exercise. Journal of Applied Physiology 93: 1280-1286. https://doi.org/10.1152/japplphysiol.01270.2001
-
Tsakiris, S. and Deliconstantinos, G., 1984. Influence of phosphatidylserine on (Na+ + K+)-stimulated ATPase and acetylcholinesterase activities of dog brain synaptosomal plasma membranes. Biochemical Journal 220: 301-307. https://doi.org/10.1042/bj2200301
-
Tsuda, Y., Murakami, R., Yamaguchi, M. and Seki, T., 2020. Acute supplementation with an amino acid mixture suppressed the exercise-induced cortisol response in recreationally active healthy volunteers: a randomized, double-blinded, placebo-controlled crossover study. Journal of the International Society of Sports Nutrition 17: 39. https://doi.org/10.1186/s12970-020-00369-2
-
Urhausen, A., Kullmer, T. and Kindermann, W., 1987. A 7-week follow-up study of the behaviour of testosterone and cortisol during the competition period in rowers. European Journal of Applied Physiology and Occupational Physiology 56: 528-533. https://doi.org/10.1007/BF00635365
-
Vance, J.E. and Steenbergen, R., 2005. Metabolism and functions of phosphatidylserine. Progress in Lipid Research 44: 207-234. https://doi.org/10.1016/j.plipres.2005.05.001
-
Vazzana, I., Rizzo, M., Dara, S., Niutta, P.P., Giudice, E. and Piccione, G., 2014. Haematological changes following reining trials in Quarter horses. Acta Scientiae Veterinariae 42: 1171.
'Haematological changes following reining trials in Quarter horses ' () 42 Acta Scientiae Veterinariae : 1171.
-
Williams, M., Raven, P.B., Fogt, D.L. and Ivy, J.L., 2003. Effects of recovery beverages on glycogen restoration and endurance exercise performance. Journal of Strength and Conditioning Research 17: 12-19. https://doi.org/10.1519/1533-4287(2003)017<0012:eorbog>2.0.co;2
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Ergogenic effects of phosphatidylserine alone and combined with branched-chain amino acids in trained rats
in Comparative Exercise PhysiologySearch for other papers by J. Costa Guimarães in
Current site
Google Scholar
PubMed
Search for other papers by A.L. Cordeiro in
Current site
Google Scholar
PubMed
Search for other papers by K.S. Cruz Borbely in
Current site
Google Scholar
PubMed
Search for other papers by E. de Oliveira Barreto in
Current site
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PubMed
Search for other papers by P.P. Menezes Scariot in
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PubMed
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Current site
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PubMed
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Search for other papers by G.G. de Araujo in
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PubMed
Acute phosphatidylserine (PS) or branched-chain amino acids (BCAA) supplements alone may have an adrenocorticotropic hormone, cortisol suppressive effect and increase the testosterone/cortisol ratio, but the associated effect of these supplements during a period of high-intensity physical stress is not yet known. The study investigated the effects of chronic PS supplementation alone and combined with BCAA during high-intensity interval training (HIIT) on training volume tolerance, anabolic-catabolic balance and stress biomarkers in rats. Thirty-three rats were separated into: placebo (PLA, n=11), PS alone (n=11) and combined with BCAA (PSBCAA, n=11). Groups performed swimming sessions of HIIT (5 series × 1 min × 1 min recovery; external load equivalent to 13% of body mass) and nine recovery sessions of moderate-intensity training (30 min at 5% of body mass) alternately. One-way ANOVA was used to compare biochemical variables and two-way ANOVA was calculated to compare training volume. Training volume performed (TVP) was higher in first, fourth, fifth, sixth, and eighth HIIT sessions in the PS group in comparison to PLA (P<0.05). TVP was higher in the fourth session in PSBCAA compared to PLA. There were no differences in TVP during the sessions between PS and BCAA groups. Creatine kinase (CK) was lower in PSBCAA in comparison to PS alone (P=0.03) and PLA (P=0.04) after the experimental period. Testosterone concentration was enhanced in PSBCAA group compared to PLA (P=0.01); testosterone/corticosterone ratio was higher in PSBCAA compared to PS (P=0.05) and PLA (P=0.004) after protocol. PS combined with BCAA increases testosterone concentration and testosterone/corticosterone ratio, demonstrating an enhancement of anabolic state in trained rats.
| Insgesamt | Letzte 365 Tage | In den letzten 30 Tagen | |
|---|---|---|---|
| Aufrufe von Kurzbeschreibungen | 605 | 212 | 40 |
| Gesamttextansichten | 17 | 1 | 0 |
| PDF-Downloads | 10 | 1 | 0 |
